Results 71 to 80 of about 70,219 (338)

Three‐Component Synthesis of γ‐Amino Esters with α‐Quaternary Carbon Centers via NHC/Photoredox Dual Catalysis

Advanced Synthesis &Catalysis, EarlyView.
γ‐Amino acid derivatives with an α‐quaternary center are prevalent in medicinally important compounds. A dual N‐heterocyclic carbene/photocatalytic pathway is developed for the three‐component synthesis of α, α ‐disubstituted γ‐amino esters. This methodology allows for the rapid synthesis of diverse libraries of γ‐amino esters in good yields.
Adam X. Wayment, Karl A. Scheidt
wiley   +1 more source

Plasmacytoma of the Sternum with Amyloid Deposition – A Cytological Diagnosis

Archives of Medicine and Health Sciences
Plasmacytoma with amyloid deposition to be diagnosed on cytology is rare. In the absence of typical clinical presentation and radiological findings, the diagnosis of plasmacytoma may not be suspected.
Durre Aden, Prajwala Gupta, Purnima Paliwal, Minakshi Bhardwaj   +3 more
doaj   +1 more source

Photocatalytic Polyene Cyclization to Cyclopentyl Thioethers with Consecutive Quaternary Centers in Fluorinated Alcohols

Advanced Synthesis &Catalysis, EarlyView.
A photocatalytic strategy enables efficient cyclization of polyenes to cyclopentyl thioethers with consecutive all‐carbon quaternary centers. Using 2,4,6‐triphenylpyrylium tetrafluoroborate in 1,1,1,3,3,3‐hexafluoroisopropanol, the method proceeds via a thiyl radical mechanism, offering high yields and good diastereoselectivities.
Nicolás Rascón, Aniruddha Biswas, Tanja Gulder   +2 more
wiley   +1 more source

Treatment of Isolated Sternal Fracture with Ultrasound-Guided Paravertebral Nerve Block: a Case Report and Literature Review [PDF]

Kosin Medical Journal, 2019
In the case of isolated sternal fractures, conservative treatment with analgesics is common, but pain can persist for more than 10 weeks, which can significantly interfere with daily life.
Jun-Mo Park, Hyunjeong Kim
doaj   +1 more source

Harnessing Vinylogy with Radicals: Photoinduced γ‐Benzylation Reactions of 2‐Silyloxyfurans

Advanced Synthesis &Catalysis, EarlyView.
Two radical‐mediated benzylations of 2‐silyloxyfurans, promoted by visible light and suitable photoredox catalysts have been disclosed. A broad scope of γ‐benzyl butenolides was obtained in one step, some of which were used as strategic precursors to bio‐valuable chiral butanolides.
Enrico Marcantonio, Debora Guazzetti, Luca Aimi, Kelly Bugatti, Pedro Mena, Marco Giannetto, Simone Fortunati, Andrea Sartori, Lucia Battistini, Leonardo Andreoni, Marco Lombardo, Franca Zanardi, Claudio Curti   +12 more
wiley   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

Advanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Giant chondrosarcoma of the sternal body: case report [PDF]

Revista Brasileira de Cirurgia Plástica
Chest wall tumors are relatively uncommon, representing 1 to 2% of all neoplasms, and approximately 5% of thoracic neoplasms. Sarcomas are rare tumors with heterogeneous presentation.
José Dalvo Maia, Antero Gomes, Ryan Nogueira Lima, Maria de Fátima de Brito Coutinho Nogueira Lima   +3 more
doaj   +1 more source

C(sp3)─S Bond Formation via the Synergy of Oxidative With Reductive Photocatalysts Through Photoredox and Dual Hydrogen Atom Transfer Processes

Advanced Science, EarlyView.
The research reveals that polysulfide anions (K2Sx), which serve as reducing catalysts, can also effectively act as sulfur reagents, providing the formation of C(sp3)─S bonds through photoredox catalysis with an oxidative photocatalyst tetrabutylammonium decatungstate (TBADT) and dual hydrogen atom transfer (DHAT) process.
Chao Zhou, Qianli Liang, Xinyi Zhu, Xue Zhang, Limei Liu, Yicheng Zhang, Jie Liu, Xiaoyu Xie, Lei Wang   +8 more
wiley   +1 more source

Gross anatomical features of the sternum of green-winged macaw (Ara Chloroptera)

, 2015
The present study was conducted on the sternum of an eight year old, male Green-winged Macaw. The sternum was quadrilateral with dorsal concave and ventral convex surfaces and four borders. The dorsal surface presented numerous pneumatic foramina.
A. Sreeranjini, N. Ashok, V. Indu, K. Lucy, S. Maya, J. J. Chungath   +5 more
semanticscholar   +1 more source