Results 61 to 70 of about 674,235 (211)

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

open access: yes, 2001
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co-repressors,
Indarto, Dono, Izawa, Masao
core  

Steroid induction of low-affinity glucocorticoid binding sites in rat liver microsomes

open access: yes, 1989
Rat liver contains two glucocorticoid binding sites: the high-affinity or glucocorticoid receptor (GR) and the low-affinity glucocorticoid binding sites, or LAGS.
Chirino, R.   +5 more
core   +1 more source

Admission steroid use, serum albumin level, and endoscopic severity predict intravenous steroid failure in patients with acute severe ulcerative colitis

open access: yes, 2021
Background and Aim: Corticosteroid therapy fails in about 40% of patients with acute severe ulcerative colitis (ASUC). It is important to develop criteria that can predict steroid failure earlier. Our aim was to identify variables at admission (clinical,
Mohsen, W   +3 more
core   +1 more source

Cedrol mitigates hepatic lipid accumulation and adipocyte hypertrophy induced by corticosteroids through the inhibition of glucocorticoid receptor activity

open access: yesScientific Reports
Cedrol is a sesquiterpene alcohol derived from ginger and cedar oil. Cedrol has multiple pharmacological effects such as sedation, promoting hair growth, decreasing blood pressure and reducing obesity.
Minghui Shu, Pan Wang
doaj   +1 more source

Profile of bile acid subspecies is similar in blood and follicular fluid of cattle

open access: yesVeterinary Medicine and Science, 2020
The composition of follicular fluid (FF) has an impact on the developmental capacity of the oocyte and the resulting embryo. FF is composed of blood plasma constituents which cross the blood follicular barrier and the secretory components of granulosa ...
Carina Blaschka   +3 more
doaj   +1 more source

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]

open access: yes, 2010
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
core  

Computational Analysis of Microtubule-Mediated Saltatory Neuroelectrical Transmission: A Theoretical Exploration

open access: yesBiophysica
It was recently postulated that neural microtubules (neuro-MTs), which are densely packed inside axons and dendrites, are vacuum cylindrical nanotubes that can mediate neuroelectrical transmission with a unique form of quasi-superconductivity.
Yong Xiao Yang, Bao Ting Zhu
doaj   +1 more source

Steroid-sparing Strategies: Other Combinations

open access: yes, 2008
In this chapter we will analyse the scientific and clinical rationale of using other steroid-sparing strategies in the treatment of asthma and/or chronic obstructive pulmonary disease (COPD), excluding long-acting inhaled (β2-agonists and kinase ...
PAPI, Alberto, ITO K, CARAMORI, Gaetano
core   +1 more source

Sleep pathology and use of anabolic androgen steroids among male weightlifters in Norway

open access: yesBMC Psychiatry
Use of anabolic androgenic steroids (AAS) causes drastic changes in hormonal milieu and is associated with a range of medical and psychological consequences. Sleep pathology is a common side-effect of AAS use but few have studied these relations.
Sandra Klonteig   +2 more
doaj   +1 more source

High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency[S]

open access: yesJournal of Lipid Research, 2015
Steroid sulfatase (STS) deficiency is the underlying cause of the skin condition known as recessive X-linked ichthyosis (RXLI). RXLI patients show scales on their skin caused by high concentrations of cholesterol sulfate (CS), as they are not capable of ...
Alberto Sánchez-Guijo   +5 more
doaj   +1 more source

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