Results 71 to 80 of about 674,235 (211)

Structural insights into prolactin-releasing peptide receptor signaling and G-protein coupling selectivity

Cell Reports
Summary: Prolactin-releasing peptide receptor (PrRPR), a notable member of the class A peptide-GPCR (G-protein-coupled receptor) family, regulates diverse physiology functions upon activation by PrRP.
Zhangsong Wu, Chen Qiu, Yiming Liu, Xiaoyi Yan, Qiaohui Li, Shirui Jiang, Jun Xu, Xin Pan, Fang Ye, Zhiyi Zhang, Peiruo Ning, Binghao Zhang, Lezhi Xu, Bangning Cheng, Xufu Xiang, Chungen Qian, Yang Du, Geng Chen   +17 more
doaj   +1 more source

Estrogen-mediated regulation of steroid metabolism in rat glial cells; effects on neurosteroid levels via regulation of CYP7B1-mediated catalysis

, 2015
Many neuroactive steroids, including dehydroepiandrosterone (DHEA), pregnenolone, 27-hydroxycholesterol and 17 beta-estradiol, are known to affect development and function of the brain and nervous system.
Wicher, Grzegorz,, Norlin, Maria,
core   +1 more source

Steroid sulfate-sulfatases in the human benign prostatic hyperplasia -BPH-

, 2022
Estrone sulfate-sulfohydrolase (E1S) and dehydroepiandrosterone sulfate-sulfohydrolase (DHEAS-S) were studied in epithelial and stromal cells of 7 human BPHs.
Bartsch, W., Molwitz, T., Voigt, K.-D.
core   +1 more source

Three‐year follow‐up of the use of a levonorgestrel‐releasing intrauterine system in hormone replacement therapy

Acta Obstetricia et Gynecologica Scandinavica, 1997
Background. The efficacy of a levonorgestrel‐releasing intrauterine system in opposing endometrial proliferation and in preventing bleeding was studied in peri‐ and postmenopausal women receiving estrogen replacement therapy. Methods.
Satu Suhonen, Teddy Holmström, Pekka Lähteenmäki   +2 more
doaj   +1 more source

Structural studies of two solid steroid compounds [PDF]

, 2006
Polymorphism (including solvated solid forms) is relatively common among steroids.Understanding the physical properties of each polymorph/ solvate is important for evaluating their relative stability and dissolution rates (related to bioavailability). In
Othman, Abdullah
core  

Cholesterol at the Center of Alzheimer’s Disease: A Unifying Hypothesis on the Pathogenic Mechanism

Molecules
It is hypothesized that in most cases of sporadic late-onset Alzheimer’s disease (LOAD), the abnormally elevated cholesterol level in brain neurons represents a critical causative factor that drives the pathogenic processes of LOAD.
Bao Ting Zhu
doaj   +1 more source

Steroid-induced psychosis

Steroid-induced ...
Fesochi Atulayo (20935214), Iresha Perera (20935211), Malcolm Forbes (13085907)   +2 more
core  

Molecular Mechanism for the Selective Presentation of Antigenic Peptides by Major Histocompatibility Complex Class I and Class II Molecules: A Hypothesis

Current Issues in Molecular Biology
The major histocompatibility complex (MHC) class I and class II molecules (abbreviated as MHC-I and MHC-II, respectively) are specialized in antigen presentation.
Bao Ting Zhu
doaj   +1 more source

Psychological traits associated with anabolic androgenic steroid use and dependence: an exploratory cross-sectional study among female athletes

BMC Women's Health
Background Anabolic–androgenic steroids (AAS) are commonly taken to increase muscle size and enhance performance. However, AAS can lead to many adverse effects, including challenges with mental health and behavior.
Morgan Scarth, Ingrid Amalia Havnes, Marie Lindvik Jørstad, Astrid Bjørnebekk   +3 more
doaj   +1 more source

β-Cyclodextrin Inclusion Complexes of 20-Hydroxyecdysone Derivatives: Synthesis, NMR Characterization, and In Vitro/In Vivo Evaluation of Antioxidant, Hepatoprotective, and Antimicrobial Activities

Pharmaceuticals
Background/Objectives: For the first time, water-soluble encapsulated forms of 20-hydroxyecdysone were synthesized as clathrate complexes with β-cyclodextrin.
Borash Tuleuov, Aizhan Zeinuldina, Aidana Bazarkhankyzy, Aizhan Kozhanova, Bakhtiyar Temirgaziyev, Saniya Dyussekeyeva, Lyazzat Abulyaissova, Nurgul Askarova, Aliya Temirbekova, Zhanar Tekebayeva, Ardak Sapiyeva, Sergazy Adekenov   +11 more
doaj   +1 more source