Results 1 to 10 of about 6,183 (145)

Embryotoxicity and Teratogenicity of Steroidal Saponin Isolated from Ophiopholis mirabilis [PDF]

open access: yesToxics, 2023
Benthic invertebrates produce secondary metabolites that serve as defenses against consumers and promote their fitness. To explore the chemical defense in marine benthic echinoderms, the chemical constituents of Ophiopholis mirabilis were investigated. A
Qian Xu   +11 more
doaj   +2 more sources

A Novel Cytotoxic Steroidal Saponin from the Roots of Asparagus cochinchinensis [PDF]

open access: yesPlants, 2021
A new steroidal saponin, 26-O-β-d-glucopyranosyl-(25R)-furost-5-ene-3β,22α,26-triol 3-O-(1−4)-β-d-glucopyranosyl-α-l-rhamnopyranosyl-(1−2)-[α-l-rhamnopyranosyl-(1−4)]-β-d-glucopyranoside [asparacochioside A (1)] was isolated from a hot water extract of ...
Ji-Young Kim   +4 more
doaj   +2 more sources

Steroidal saponin profiles and their key genes for synthesis and regulation in Asparagus officinalis L. by joint analysis of metabolomics and transcriptomics [PDF]

open access: yesBMC Plant Biology, 2023
Background Asparagus officinalis L. is a worldwide cultivated vegetable enrichened in both nutrient and steroidal saponins with multiple pharmacological activities.
Qin Cheng   +8 more
doaj   +2 more sources

RNA-sequencing-based transcriptome and biochemical analyses of steroidal saponin pathway in a complete set of Allium fistulosum-A. cepa monosomic addition lines. [PDF]

open access: yesPLoS ONE, 2017
The genus Allium is a rich source of steroidal saponins, and its medicinal properties have been attributed to these bioactive compounds. The saponin compounds with diverse structures play a pivotal role in Allium's defense mechanism.
Mostafa Abdelrahman   +10 more
doaj   +2 more sources

Isolation of dioscin-related steroidal saponin from the bulbs of Allium paradoxum L. with leishmanicidal activity [PDF]

open access: yesResearch in Pharmaceutical Sciences, 2018
Alliums are rich sources of steroidal saponins, flavonoids, and sulphoric compounds of which steroidal saponins have recently received more attention due to their important pharmacological activities. Allium paradoxum L.
Fatemeh Rezaee   +2 more
doaj   +2 more sources

Multi-dimensional identification and quality evaluation of Paris polyphylla cultivated populations using morphological, molecular, cytological and metabolic traits [PDF]

open access: yesFrontiers in Plant Science
IntroductionParis polyphylla is an endangered medicinal herb valued for its steroidal saponins, yet the phenotypic stability, genetic diversity, and quality differentiation of cultivated populations remain insufficiently understood.MethodsIn this study ...
Jinhui Jiang   +13 more
doaj   +2 more sources

Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat [PDF]

open access: yesMolecules, 2015
A rapid, selective and sensitive UPLC-MS/MS assay was established to determine the plasma concentrations of four steroidal saponins. Sprague-Dawley rats were allocated to four groups which were orally administered Anemarrhena asphodeloides extracts (ASE),
Zhishu Tang   +7 more
doaj   +2 more sources

Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum

open access: yesFrontiers in Plant Science, 2021
Fenugreek (Trigonella foenum-graecum), a pharmacologically important herb, is widely known for its antidiabetic, hypolipidemic, and anticancer effects. The medicinal properties of this herb are accredited to the presence of bioactive steroidal saponins ...
Jianghong Gao   +4 more
doaj   +1 more source

Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L.

open access: yesResearch in Pharmaceutical Sciences, 2022
Background and purpose: Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds.
Narges Vakili   +2 more
doaj   +1 more source

Paris polyphylla Sm. Induces Reactive Oxygen Species and Caspase 3-Mediated Apoptosis in Colorectal Cancer Cells In Vitro and Potentiates the Therapeutic Significance of Fluorouracil and Cisplatin

open access: yesPlants, 2023
Paris polyphylla Sm. (Melanthiaceae) is an essential, vulnerable herb with a wide range of traditional applications ranging from fever to cancer in various communities. The use of P. polyphylla in India is limited to traditional healers.
Vimi Kshetrimayum   +6 more
doaj   +1 more source

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