Results 201 to 210 of about 59,068 (232)

STEROIDOGENESIS IN ADRENAL CELLS

Journal of Steroid Biochemistry, 1974
Abstract It has been found that a potential exogenous steroid precursor such as cholesterol is not utilized by inhomogeneous rat adrenal cell suspensions, even under stimulation by ACTH or cAMP, unless exogenous NADPH or NADPH generation is provided.
R. Neher, A. Milani
openaire   +1 more source

STEROIDOGENESIS IN EQUINE TESTIS

Acta Endocrinologica, 1970
ABSTRACT When the cell-free homogenates (supernatant fluid at 800 × g) and the supernatant fluid at 10 000 × g of equine testis were incubated with 4-14C-labelled progesterone and 17α-hydroxyprogesterone, radioactive androstenedione and testosterone were isolated as the metabolites.
R, O, B, Tamaoki
openaire   +2 more sources

The development of steroidogenesis

The American Journal of Medicine, 1972
Abstract Early in human development steroid-producing cells appear; the first of these are the trophoblastic cells of the placenta. Although active in the production of progesterone and estrogens, the syncytiotrophoblast lacks several key enzymes in steroid metabolism and therefore the placenta is an incomplete steroidogenic tissue.
openaire   +2 more sources

Peroxisomes in adrenal steroidogenesis

Microscopy Research and Technique, 1997
Peroxisomes, cytoplasmic organelles limited by a single membrane and with a matrix of moderate electron density, are present in a great number of cells, namely in adrenal cortex and other steroid-secreting organs. Presently peroxisomes are considered to be involved in important metabolic processes.
M M, Magalhães, M C, Magalhães
openaire   +2 more sources

Ascorbic Acid in Steroidogenesis

Nature, 1967
THE adrenal glands contain the highest concentration of ascorbic acid of any tissue in the body. Changes in the concentrations of ascorbic acid and cholesterol are related to steroid secretion in the adrenal1. Although it has been suggested that ascorbic acid might play a primary part in Steroidogenesis2, its physiological role in the adrenal has not ...
openaire   +2 more sources

Placental and Fetal Steroidogenesis

2009
Steroid hormones are essential for maintenance of pregnancy and fetal development. The expression and catalytic activity of the key steroidogenic enzymes involved in the production of progesterone and estrogens increase during pregnancy, and there is an intricate communication between the mother, the placenta, and the fetus in order to maintain a ...
openaire   +2 more sources

Regulation of Ovarian Steroidogenesis

1987
The surge of interest in comparative endocrinology over the last thirty years has advanced our knowledge of gonadal steroidogenesis in nonmammalian vertebrates. In particular, the last decade has seen major advances thanks to the isolation and characterization of various compounds and the advent of more sensitive methods for hormone measurement.
Chieffi G, PIERANTONI, Riccardo
openaire   +2 more sources

Cellular Organization for Steroidogenesis

1984
Publisher Summary This chapter provides an overview of cellular organization for steroidogenesis. There are two approaches: purification and reconstitution, which resemble the classical steps of organic chemistry—namely, isolation, and synthesis. It is clear that the methods of cell biology must be applied to steroidogenesis—that is, it is necessary ...
openaire   +2 more sources

Neurosteroids: Regional Steroidogenesis

2014
An enzymatic activity of cytochrome P450 was first identified as a component of adrenal steroidogenesis by Estabrook and his coworkers in 1963. The adrenal glands and gonads synthesize large amounts of steroid hormones and secrete them for systemic circulation. Two decades later, regional steroidogenesis in the brain was well established by Baulieu and
Takeshi Yamazaki, Yasuhiro Ishihara
openaire   +1 more source

Steroidogenesis

Journal of Endocrinology, 1993
openaire   +1 more source