Results 211 to 220 of about 43,028 (255)

STEROIDOGENESIS IN ADRENAL CELLS

Journal of Steroid Biochemistry, 1974
Abstract It has been found that a potential exogenous steroid precursor such as cholesterol is not utilized by inhomogeneous rat adrenal cell suspensions, even under stimulation by ACTH or cAMP, unless exogenous NADPH or NADPH generation is provided.
R. Neher, A. Milani
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STEROIDOGENESIS IN EQUINE TESTIS

Acta Endocrinologica, 1970
ABSTRACT When the cell-free homogenates (supernatant fluid at 800 × g) and the supernatant fluid at 10 000 × g of equine testis were incubated with 4-14C-labelled progesterone and 17α-hydroxyprogesterone, radioactive androstenedione and testosterone were isolated as the metabolites.
R, O, B, Tamaoki
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Disorders of Adrenal Steroidogenesis

Pediatric Clinics of North America, 1987
This article reviews the processes of normal adrenal function, including the three main classes of hormones. From there it describes reduced or absent enzyme activity in the stages of steroid synthesis, and proceeds to outline the enzyme deficiency responsible for the clinical effects that manifest themselves in characteristic metabolic disturbances.
S, Drucker, M I, New
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Role of Mitochondria in Steroidogenesis

2010
All steroids are made from cholesterol by a complex array of enzymes that includes cytochrome P450 enzymes in both the mitochondria and endoplasmic reticulum. The structures and mechanisms of catalysis by the mitochondrial and endoplasmic reticulum P450s are very similar, but their electron transport mechanisms differ.
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Peroxisomes in adrenal steroidogenesis

Microscopy Research and Technique, 1997
Peroxisomes, cytoplasmic organelles limited by a single membrane and with a matrix of moderate electron density, are present in a great number of cells, namely in adrenal cortex and other steroid-secreting organs. Presently peroxisomes are considered to be involved in important metabolic processes.
M M, Magalhães, M C, Magalhães
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Cellular Organization for Steroidogenesis

1984
Publisher Summary This chapter provides an overview of cellular organization for steroidogenesis. There are two approaches: purification and reconstitution, which resemble the classical steps of organic chemistry—namely, isolation, and synthesis. It is clear that the methods of cell biology must be applied to steroidogenesis—that is, it is necessary ...
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Gossypol inhibits testicular steroidogenesis

Fertility and Sterility, 1981
Gossypol, a compound isolated from cottonseed, has been used in the People's Republic of China as an antifertility agent in men. It was reported that gossypol is highly effective in reducing sperm count. Our study suggests that gossypol inhibits luteinizing hormone, 8-bromo-adenosine 3',5'-monophosphate-induced testosterone formation, and the ...
Lin, T. U., Murono, Eisuke P., Osterman, Juraj, Nankin, Howard R., Coulson, Patricia B.   +4 more
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Placental and Fetal Steroidogenesis

2009
Steroid hormones are essential for maintenance of pregnancy and fetal development. The expression and catalytic activity of the key steroidogenic enzymes involved in the production of progesterone and estrogens increase during pregnancy, and there is an intricate communication between the mother, the placenta, and the fetus in order to maintain a ...
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Steroidogenesis in the Mammalian Testis

Endocrine Reviews, 1980
THE MAMMALIAN testis has long been known to synthesize androgens, primarily testosterone, from several steroidal and nonsteroidal precursors. Some of the precursors that are converted to testosterone include acetate (1), cholesterol (2), pregnenolone1 (3, 4), and progesterone (5).
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Regulation of Ovarian Steroidogenesis

1987
The surge of interest in comparative endocrinology over the last thirty years has advanced our knowledge of gonadal steroidogenesis in nonmammalian vertebrates. In particular, the last decade has seen major advances thanks to the isolation and characterization of various compounds and the advent of more sensitive methods for hormone measurement.
Chieffi G, PIERANTONI, Riccardo
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