Results 181 to 190 of about 31,449 (215)
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STEROIDOGENESIS IN EQUINE TESTIS
Acta Endocrinologica, 1970ABSTRACT When the cell-free homogenates (supernatant fluid at 800 × g) and the supernatant fluid at 10 000 × g of equine testis were incubated with 4-14C-labelled progesterone and 17α-hydroxyprogesterone, radioactive androstenedione and testosterone were isolated as the metabolites.
R, O, B, Tamaoki
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Role of Mitochondria in Steroidogenesis
2010All steroids are made from cholesterol by a complex array of enzymes that includes cytochrome P450 enzymes in both the mitochondria and endoplasmic reticulum. The structures and mechanisms of catalysis by the mitochondrial and endoplasmic reticulum P450s are very similar, but their electron transport mechanisms differ.
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Cellular Organization for Steroidogenesis
1984Publisher Summary This chapter provides an overview of cellular organization for steroidogenesis. There are two approaches: purification and reconstitution, which resemble the classical steps of organic chemistry—namely, isolation, and synthesis. It is clear that the methods of cell biology must be applied to steroidogenesis—that is, it is necessary ...
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Gossypol inhibits testicular steroidogenesis
Fertility and Sterility, 1981Gossypol, a compound isolated from cottonseed, has been used in the People's Republic of China as an antifertility agent in men. It was reported that gossypol is highly effective in reducing sperm count. Our study suggests that gossypol inhibits luteinizing hormone, 8-bromo-adenosine 3',5'-monophosphate-induced testosterone formation, and the ...
Lin, T. U. +4 more
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Ascorbic Acid in Steroidogenesis
Nature, 1967THE adrenal glands contain the highest concentration of ascorbic acid of any tissue in the body. Changes in the concentrations of ascorbic acid and cholesterol are related to steroid secretion in the adrenal1. Although it has been suggested that ascorbic acid might play a primary part in Steroidogenesis2, its physiological role in the adrenal has not ...
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Regulation of Ovarian Steroidogenesis
1987The surge of interest in comparative endocrinology over the last thirty years has advanced our knowledge of gonadal steroidogenesis in nonmammalian vertebrates. In particular, the last decade has seen major advances thanks to the isolation and characterization of various compounds and the advent of more sensitive methods for hormone measurement.
Chieffi G, PIERANTONI, Riccardo
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Steroidogenesis: Unanswered Questions
Yearbook of Paediatric Endocrinology, 2017Until the mid-1980s studies of steroidogenesis largely depended on identifying steroid structures and measuring steroid concentrations in body fluids. The molecular biology revolution radically revolutionized studies of steroidogenesis with the cloning of known steroidogenic enzymes, by identifying novel factors, and delineating the genetic basis of ...
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2012
Adrenocortical steroidogenesis is initiated by the interaction of ACTH with melanocortin receptor type 2 (MC2-R) that stimulates secretion and production of cortisol via the activation of steroidogenic enzymes and cholesterol mobilization or transport into mitochondria (Felig and Frohman 2001; Payne and Hales 2004).
Andrzej T. Slominski +5 more
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Adrenocortical steroidogenesis is initiated by the interaction of ACTH with melanocortin receptor type 2 (MC2-R) that stimulates secretion and production of cortisol via the activation of steroidogenic enzymes and cholesterol mobilization or transport into mitochondria (Felig and Frohman 2001; Payne and Hales 2004).
Andrzej T. Slominski +5 more
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Lipoproteins and the regulation of steroidogenesis
Biochemical Society Transactions, 1985E R, Simpson +3 more
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