Results 171 to 180 of about 31,449 (215)

Gene regulation of steroidogenesis

The Journal of Steroid Biochemistry and Molecular Biology, 1995
The biosynthesis of various steroid hormones in animal tissues are catalyzed by six forms of cytochrome P450 and two hydroxysteroid dehydrogenases. The tissue-specific expression of these enzymes, which are under the control of the pituitary gland and mainly regulated at the transcriptional level, determines the steroidogenesis of animal tissues ...
T, Omura, K, Morohashi
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Role of mitochondria in steroidogenesis

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
Adrenal gonadal, placental and brain mitochondria contain several steroidogenic enzymes, notably the cholesterol side chain cleavage enzyme, P450scc, which is the enzymatic rate-limiting step in steroidogenesis which determines cellular steroidogenic capacity.
Vassilios, Papadopoulos, Walter L, Miller   +1 more
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Steroidogenesis in the Mammalian Testis

Endocrine Reviews, 1980
THE MAMMALIAN testis has long been known to synthesize androgens, primarily testosterone, from several steroidal and nonsteroidal precursors. Some of the precursors that are converted to testosterone include acetate (1), cholesterol (2), pregnenolone1 (3, 4), and progesterone (5).
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Inhibition of Steroidogenesis by Cyanoketone

Gynecologic and Obstetric Investigation, 2010
The effect of cyanoketone on some steps of steroidogenesis has been studied on testicular and adrenal tissue of male Wistar rats. Pregnenolone, dehydroepiandrosterone and progesterone (4-C14) have been used as substrates. The metabolites have been separated by thin layer chromatography and identified by crystallization to constant specific activity ...
C L, Di Prisco, G, Materazzi, B, Scattolini   +2 more
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REGULATION OF STEROIDOGENESIS IN TESTIS

Journal of Steroid Biochemistry, 1974
Abstract The endogenous neutral steroids in human, boar and rat testis tissue were investigated by gas-liquid chromatography and gas chromatography-mass spectrometry. In addition, the secretion of these steroids by human testis was investigated under basal conditions as well as during human chorionic gonadotrophin (HCG) administration. In man and rat
R. Vihko, A. Ruokonen
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Disorders of Adrenal Steroidogenesis

Pediatric Clinics of North America, 1987
This article reviews the processes of normal adrenal function, including the three main classes of hormones. From there it describes reduced or absent enzyme activity in the stages of steroid synthesis, and proceeds to outline the enzyme deficiency responsible for the clinical effects that manifest themselves in characteristic metabolic disturbances.
S, Drucker, M I, New
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STEROIDOGENESIS IN ADRENAL CELLS

Journal of Steroid Biochemistry, 1974
Abstract It has been found that a potential exogenous steroid precursor such as cholesterol is not utilized by inhomogeneous rat adrenal cell suspensions, even under stimulation by ACTH or cAMP, unless exogenous NADPH or NADPH generation is provided.
R. Neher, A. Milani
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Placental and Fetal Steroidogenesis

2009
Steroid hormones are essential for maintenance of pregnancy and fetal development. The expression and catalytic activity of the key steroidogenic enzymes involved in the production of progesterone and estrogens increase during pregnancy, and there is an intricate communication between the mother, the placenta, and the fetus in order to maintain a ...
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Danazol Inhibits Steroidogenesis

Fertility and Sterility, 1977
Danazol was found to inhibit multiple enzymes of steroidogenesis directly in the pregnant mare serum (PMS)-treated hamster ovary and the rat testis and adrenal in vitro. In the PMS-treated hamster ovary, danazol inhibited 17alpha-hydroxylase, 17,20-lyase, and 3beta-hydroxysteroid dehydrogenase.
R L, Barbieri, J A, Canick, A, Makris, R B, Todd, I J, Davies, K J, Ryan   +5 more
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Peroxisomes in adrenal steroidogenesis

Microscopy Research and Technique, 1997
Peroxisomes, cytoplasmic organelles limited by a single membrane and with a matrix of moderate electron density, are present in a great number of cells, namely in adrenal cortex and other steroid-secreting organs. Presently peroxisomes are considered to be involved in important metabolic processes.
M M, Magalhães, M C, Magalhães
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