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Upadacitinib for Induction of Remission in Pediatric Ulcerative Colitis: An International Multicenter Study. [PDF]
Yerushalmy-Feler A +34 more
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Research Progress on the Effect of <i>Thesium chinense Turcz.</i> on Neurodegenerative Diseases. [PDF]
Li Z +7 more
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Leveraging molecular graphs for natural product classification. [PDF]
Prete AL +4 more
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2023
Steroids are organic compounds with four rings arranged in a precise molecular configuration and are involved in many biological functions displaying a wide spectrum of biological activities and diverse chemical reactivities. Structural modifications of the steroidal rings have attracted a considerable amount of attention recently.
Mukesh M. Mudgal, Mangesh M. Mudgal
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Steroids are organic compounds with four rings arranged in a precise molecular configuration and are involved in many biological functions displaying a wide spectrum of biological activities and diverse chemical reactivities. Structural modifications of the steroidal rings have attracted a considerable amount of attention recently.
Mukesh M. Mudgal, Mangesh M. Mudgal
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Heterocyclic steroids. Steroidal pyrimidines
Experientia, 1963Die erste Synthese eines Steroid-Analogen, in welchem Ring A zu einem Pyrimidin umgewandelt wurde, wird beschrieben. Die wichtigste Zwischenstufe 4b wurde durch Abbau von 19-nor-Testosteron gewonnen. Kondensation von 4b mit Thioharnstoff fuhrte zu 17β-Acetoxy-2,4-diazaestr-4-en-1-on-3-thion (5).
E, CASPI, D M, PIATAK
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Tetrahedron Letters, 1966
Abstract The acetylester (Ib) has been transformed into several derivatives. The direction of bromination of the 4-ketone under acid conditions has been shown as proceeding toward C-3 by the isolation of bromosteroids (Ic) and V. In addition, the 2-oxa lactone (III) has been prepared.
J.G. Westra +3 more
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Abstract The acetylester (Ib) has been transformed into several derivatives. The direction of bromination of the 4-ketone under acid conditions has been shown as proceeding toward C-3 by the isolation of bromosteroids (Ic) and V. In addition, the 2-oxa lactone (III) has been prepared.
J.G. Westra +3 more
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Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines
Steroids, 2020Steroids are components of cell membranes, signaling molecules and are a type of secondary metabolites as a result of their high impact of biological significance. The present review described the literature reports of pentacyclic steroidal pyrimidines as a type of heterocyclic steroids.
M. Monier +4 more
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Polynuclear heterocyclic systems. Part V: Heterocycles related to steroids and C‐nor‐steroids
Recueil des Travaux Chimiques des Pays-Bas, 1968AbstractThe preparation of 6‐methoxy‐2‐(2′‐oxocyclopentyl‐1‐tetralone (I) and 2‐(2′‐oxocyclopentyl)quinolizidin‐1‐one (II) is described. Diketones I and II have been converted to heterocyclic systems related to steroids and C‐nor‐steroids.
R. van Hes +3 more
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