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Synthesis of novel steroidal heterocyclic derivatives as antibacterial agents
Steroids, 2007This study aimed at the synthesis of novel structurally promising steroidal heterocycles and to elucidate the potential role of these compounds as antibacterial agents. Epi-androsterone 1 reacted with CS2 and sodium hydride in dimethylsulfoxide to yield alpha-oxoketene dithiodisodium salt 2. The non-isolable salt 2 reacted with acetyl chloride, benzoyl
Mervat M, Abdelhalim +3 more
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Synthesis of heterocyclic steroids—V
Tetrahedron, 1960G.V. Bhide, N.L. Tikotkar, B.D. Tilak
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Synthesis of Steroidal Heterocycles
HETEROCYCLES, 1977A. V. Kamernitzky, A. M. Turuta
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Building heterocyclic architectures on steroid frameworks
Steroid heterocyclic hybrids (SHHs) are a highly promising class of compounds of relevant interest in the field of drug discovery and material science. The advancement of synthetic strategies plays a key role in achieving the access to the required structural diversity of SHHs and in overcoming the bottle neck of their availability for SAR studies and ...Arcadi, Antonio +3 more
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