Results 61 to 70 of about 185,877 (187)
Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon +9 more
wiley +1 more source
IN SILICO DRUG-LIKENESS OF STEROIDAL HETEROCYCLIC DERIVATIVES
ProceedingsSteroidal bis-thiosemicarbazones and their cyclic derivatives, thiadiazolines (TDZs) and triazoline-3-thiones (TATs), were evaluated in silico (Molinspiration, pkCSM) to assess drug-likeness and pharmacokinetic properties. With the exception of cholestane-based derivatives, most compounds complied with Lipinski’s criteria or showed only a single ...
Marijana Živković +2 more
openaire +2 more sources
Progress in heterocyclic chemistry.
, 2010 Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and ...
Joule, J. A.(John Arthur) +1 more
core
Myotrophic and Androgenic Activities of Androstanazole. A New Heterocyclic Steroid
Experimental Biology and Medicine, 1960 SummaryMyotrophic and androgenic activities of androstanazole have been evaluated using immature castrated male rats. The data indicate that androstanazole is 1/7 as myotrophic and 1/33 as androgenic as testosterone propionate when both agents are administered subcutaneously, whereas it is 2 times more myotrophic than.
G O, POTTS, A L, BEYLER, D F, BURNHAM
openaire +2 more sources
The impact of nandrolone decanoate and growth hormone on biosynthesis of steroids in rats
, 2013 Growth hormone (GH) and anabolic androgenic steroids (AAS) are commonly used in sports communities. Several studies have suggested an association between GH and AAS.
Johansson, Jenny, +4 more
core +1 more source
Everything you need to know about steroids.
, 2019 Analysis: most commonly associated with cheating athletes, steroids occur naturally in our bodies and play an important role in modern ...
Ahuja, Dipali +2 more
core
Synthesis of Indole and Benzimidazole Substituted Novel 16-Arylidene Steroid Derivatives
, 2019 Novel aza-heterocyclic substituted dehydroepiandrosterone derivatives were synthesized through a three-step reaction sequence. Some new O-alkylated 4-hydroxybenzaldehydes were synthesized from the reaction of substituted benzaldehydes with dihalogen ...
SERVİ, SÜLEYMAN +2 more
core +1 more source
The Chemistry of Benzotriazole Derivatives: A Tribute to Alan Roy Katritzky
, 2016 The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental ...
core +1 more source
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives
, 2005 Three new heterocyclic ring systems were synthesized from [1,3,5]triazino[1,2-a]benzimidazole derivatives, which in turn were obtained by condensation of 2-guanidinobenzimidazole with o-substituted ...
Gianluca Pardi +15 more
core +1 more source
, 1999 The preparation of two new heterocyclic ring systems, purinobenzodiazepine and purinobenzotriazocine derivatives by the condensation of 8‐aminotheophylline or 8‐hydrazinotheophylline with o ‐carboxybenzaldehyde or o ‐carboxyacetophenone is ...
A. DA SETTIMO +11 more
core +1 more source