Results 51 to 60 of about 185,877 (187)
, 2015 Neuroactive steroids (NASs) have been shown to impact central nervous system (CNS) function through positive allosteric modulation of the GABAA receptor (GABAA-R). Herein we report the effects on the activity and pharmacokinetic properties of a series of
Scott J. Grossman (1613350) +14 more
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ChemMedChem, Volume 21, Issue 21, 12 November 2026.Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai +5 more
wiley +1 more source
Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat
Plant Biotechnology Journal, Volume 24, Issue 11, Page 5911-5926, November 2026.ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv +11 more
wiley +1 more source
FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts
European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya +2 more
wiley +1 more source
, 2008 National Hi-Tech Development Project (863 project) [2006AA09Z446, 2006DFA31100, 2006AA09Z405]; NSFC [30672607, 30600053, 40176038, 30171106]; International Cooperation Projects of BMBF-MOSTA chemical examination of the Chinese sponge Acanthella cavernosa
邱彦 +5 more
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, 2011 Steroids: The basic science and clinical aspects covers the modern understanding and clinical use of steroids. The history of steroids is richly immersed and runs long and deep.
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Development of a Method of Analysis by Gas Chromatography-Mass Spectrometry using Selected Ion Monitoring for the Measurement of Fish Sex Steroids in Water [PDF]
, 2009 A method for the analysis of testosterone, androstenedione, 5β-dihydrotestosterone, 11-ketotestosterone, estrone, 17β-estradiol, 17α-hydroxyprogesterone, 17α,20β-dihydroxy-4-pregnen-3-one, 5β-pregnane-3α,17α,20α-triol, 5β-androstane-3α,17β-diol, 5β ...
Boult, Cherie Helen
core
A novel acid catalysed cyclization - synthesis and X-ray crystal structure analysis of 8-Acetoxy-6-(2,4-Dimethoxy-5 -Bromophenyl)-3-Methyltricyclo(5,2,1,03,8)Decan-2-one [PDF]
, 1972 In connection with the total synthesis of heterocyclic steroids, we undertook the synthesis of a B-secosteroid intermediate (I) starting from 2',3,4'-trimethoxy-propiophenone [1]. Examples involving a 'B-seco' approach for the total synthesis of steroids
Ramachandra, R +3 more
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H-1 NMR determination of adulteration of anabolic steroids in seized drugs
, 2018 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Counterfeiting and adulteration of pharmaceuticals is a prevalent problem worldwide and represents a major health risk to the population, with anabolic steroids being one of the main ...
Pezza, Leonardo [UNESP] +9 more
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, 2019 Hair steroids and their ratios are believed to be reliable biomarkers reflecting the long-term exposure of circulating steroids. Hereinto, two underlying assumptions are that hair biomarkers have consistency with traditional biomarkers in saliva or urine,
Wang, Weiwen +5 more
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