Results 31 to 40 of about 9,182 (197)

Enantioselective synthesis of (+)-petromyroxol, enabled by rhodium-catalyzed denitrogenation and rearrangement of a 1-sulfonyl-1,2,3-triazole [PDF]

, 2015
Petromyroxol is a non-racemic mixture of enantiomeric oxylipids isolated from water conditioned with larval sea lamprey. The (+)-antipode exhibits interesting biological properties but only 1 mg was isolated from >100000 L of water.
Boyer, Alistair
core   +2 more sources

Peripheral edema associated with trazodone: A case reports

Psychiatry and Clinical Psychopharmacology, 2021
Peripheral edema is often associated with medical etiologies (cirrhosis, heart failure, protein deficiency, cancer, renal diseases) and drugs (NSAID, steroids, antihypertensives and immunosuppressive drugs). Trazodone is a heterocyclic antidepressant of
Gülcan Balcı, Baise Tıkır, Erol Göka   +2 more
doaj  

Ruthenium-catalyzed asymmetric reduction of isoxazolium salts : access to optically active Δ4-isoxazolines [PDF]

, 2018
A tethered MsDPEN–ruthenium catalyst reduces a series of isoxazolium salts, affording optically active Δ4-isoxazolines in moderate to good yields and enantioenrichment. The redundancy of heating or high pressures allowed for chemoselective reduction with
Chew, Renta Jonathan, Wills, Martin
core   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Systematic Review of Small-Molecule Compounds, Analytical Techniques, and Pharmacological Activities of Animal-derived Traditional Chinese Medicines

World Journal of Traditional Chinese Medicine
Animal-derived traditional Chinese medicines (ATCMs), which are prepared from whole animals, organs, or physiological and pathological products, have gained wide recognition and have become an integral part of traditional Chinese medicine in recent years.
Han-Ze Wang, Yan Zhang, Jia-Yuan Li, Qi-Rui Bi, Meng-Meng Li, Lin Feng, Ya-Jun Qiao, Chun-Xiang Liu, Yan-Zhen Wen, Yong-Yong Zhou, Fu-Yu Xiong, Yang Yang, Qin-Hua Chen, De-An Guo   +13 more
doaj   +1 more source

Steps in immunosuppression for renal transplantation [PDF]

, 1983
The authors provide a historical survey of the immunosuppressive agents that have been used to prevent allograft rejection.
Hakala, TR, Rosenthal, JT, Starzl, TE
core  

Sir John Cornforth AC CBE FRS: his synthetic work [PDF]

, 2015
Sir John Cornforth’s work on the synthesis of cholesterol and penicillamine, on the chemistry of oxazoles, the stereochemistry of the synthesis of alkenes, the synthesis of abscisic acid and of dibenzophospholes as mimics of enzyme action, is ...
Abraham E.P., Abraham E.P., Abraham E.P., Callow R.K., Cardwell H.M.E., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., Cornforth J.W., James R. Hanson, Rupert Purchase   +15 more
core   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]

, 2016
The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani, Baltezor, Michael, Butte, Atul J, Chen, Bin, Flynn, Colleen A, Godwin, Andrew K, Hyter, Stephen, Ma, Yan, Neville, Kathleen A, Pessetto, Ziyan Y, Rosenthal, Howard G, Weir, Scott J   +11 more
core   +3 more sources

Substituent‐Controlled Ring Opening of 1‐Substituted Benzocyclobutenes: Electronic Structure and Diradical Character of Ortho‐Quinodimethane Intermediates

Chemistry – A European Journal, EarlyView.
Experimental and computational studies elucidate how the electronic nature of substituents controls the ring‐opening temperature and diradical character of 1‐substituted benzocyclobutenes, enabling the rational design of o‐quinodimethane‐based synthetic transformations.
Magali Dallegre, Imen Abid, Roselyne Rosas, Maxime Dousset, Gaëlle Chouraqui, Laurent Commeiras, Didier Siri, Didier Gigmes, Anthony Kermagoret   +8 more
wiley   +1 more source