Results 11 to 20 of about 173,508 (193)

Studies of novel nitro-substituted nitrogen heterocyclic compounds [PDF]

, 2001
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The novel candidate high energy insensitive explosive; 2,5-diamino-3,6-dinitropyrazine (ANPZ-i) has been prepared in acceptable overall yield.
Philbin, Simon Patrick
core   +7 more sources

Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans [PDF]

, 2014
The marine sponge Haliclona simulans collected from the Irish Sea yielded two new steroids: 24-vinyl-cholest-9-ene-3β,24-diol and 20-methyl-pregn-6-en-3β-ol,5a,8a-epidioxy, along with the widely distributed 24-methylenecholesterol.
Ooi, Thengtheng, Kennedy, Jonathan, Clements, Carol, Abbott, Gráinne, Viegelmann, Christina, Young, Louise, Parker, Jennifer, Dobson, Alan D W, Edrada-Ebel, RuAngelie   +8 more
core   +4 more sources

Impact of Inoculation Strategy on <i>Dendrobium nobile</i> Lindl. Rice Wine Quality Through the Use of <i>Saccharomyces cerevisiae</i> FBKL2.8022 and <i>Wickerhamomyces anomalus</i> FBKL2.8023. [PDF]

Food Sci Nutr
This graphical abstract compares four fermentation strategies for D. nobile rice wine: simultaneous inoculation without D. nobile (SW), simultaneous inoculation with D. nobile (DnSW), sequential inoculation without D. nobile (WS), and sequential inoculation with D. nobile (DnWS). Simultaneous inoculation (SW/DnSW) enhanced volatile compound content (up
Gan H, Huang G, Zhang L, Cen L, Dai Y, Qiu S, Wang X, Wei C.   +7 more
europepmc   +2 more sources

Computational Evaluation of Heterocyclic Steroids: Physicochemical and Pharmacoki-netic Insights [PDF]

Records of Pharmaceutical & Biomedical Sciences
Cancer remains a significant global health challenge, driving the need for novel therapeutic agents with enhanced efficacy and reduced side effects.
Shadeed Gad, Fouad Bardi, Mohammed Amran, Norehan Ghourab, Mohamed Tantawy, Hossam elsawy   +5 more
doaj   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Eser, Daniela, Eser D., Baghai, Thomas C., Schule C., Romeo, Elena, Baghai T. C., Schuele, Cornelius, Rupprecht R., Rupprecht, Rainer, Eser D., Schule C., Baghai T.C., Romeo E., Rupprecht R.   +9 more
core   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, EarlyView.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +2 more sources

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z‐Alkenes

Angewandte Chemie, EarlyView.
One catalyst for two products: CO acts as a molecular trigger for adaptive alkyne hydrogenation using supported Pd nanoparticles. The catalyst reversibly switches between the formation of alkanes under H2 and Z‐alkenes under H2/CO for 37 structurally diverse alkynes.
Manisha Durai, Lachlan Sharp‐Bucknall, Tim Alexander Schubert, Jacob Johny, John‐Tommes Krzeslack, Walid Hetaba, Walter Leitner, Alexis Bordet   +7 more
wiley   +2 more sources

Prediction and Analysis of Active Components in Tea Stem Fermented Product Based on Network Pharmacology [PDF]

Chaye kexue
Tea stem has a significant impact on the sensory quality for Fucha fermentation product. To explore the active ingredients and targets of tea stems in Fucha, Aspergillus cristatus LJSC.2006 (GenBank accession number: MZ147020) was used to ferment tea ...
HE Haotian, XIAO Juanjuan, TANG Yiyu, LUO Mi, LIU Zhonghua, YU Lijun
doaj   +1 more source

Boranes in Organic Chemistry 1. О±-Carbonylalkyl- and ОІ-Oxyalkylboranes in Organic Synthesis

Eurasian Chemico-Technological Journal, 2002
This review is devoted to the synthesis of a-carbonylalkyl- and ОІ-hydroxy-alkyl boranes and their use in organic synthesis. a-Carbonyl-alkylboranes include several heteroatomic compounds, in particular, [1.2.3]-diazaborinines, uracyl boronic acids, and
V.M. Dembitsky, G.A. Tolstikov, M. Srebnik   +2 more
doaj   +1 more source