Results 41 to 50 of about 16,062 (239)

Cholesterol, bile acid, and lipoprotein metabolism in two strains of hamster, one resistant, the other sensitive (LPN) to sucrose-induced cholelithiasis1

Journal of Lipid Research, 2000
A comprehensive study of cholesterol, bile acid, and lipoprotein metabolism was undertaken in two strains of hamster that differed markedly in their response to a sucrose-rich/low fat diet.
Jacqueline Férézou, Murielle Combettes-Souverain, Maâmar Souidi, Jeffery L. Smith, Nathalie Boehler, Fabien Milliat, Erik Eckhardt, Géraldine Blanchard, Michel Riottot, Colette Sérougne, Claude Lutton   +10 more
doaj   +1 more source

Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway [PDF]

, 2020
Diatoms are ubiquitous microalgae that have developed remarkable metabolic plasticity and gene diversification. Here we report the first elucidation of the complete biosynthesis of sterols in the lineage.
, Angela, d’Ippolito, Giuliana, Fontana, Angelo, GALLO, CARMELA, LANDI, SIMONE, MANZO, EMILIANO, Nuzzo, Genoveffa, Sardo &   +7 more
core   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Groen, A.K., Hageman, J., Herrema, H.J., Kuipers, F.   +3 more
core   +6 more sources

Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol.

Journal of Lipid Research, 1993
Sterol 27-hydroxylase, the mitochondrial enzyme that catalyzes the first step in oxidation of the sterol side chain in hepatic bile acid synthesis, also catalyzes the synthesis of 27-hydroxycholesterol from cholesterol.
B Petrack, B J Latario
doaj   +1 more source

Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships [PDF]

, 2017
The Integral Membrane Histidine Motif-containing Enzymes (IMHME) are a class of binuclear non-heme iron proteins widely distributed among prokaryotes and eukaryotes.
Cid, Nicolás Gonzalo, Elguero, María Eugenia, Montes, María Guadalupe, Nudel, Berta Clara, Nusblat, Alejandro David, Sánchez Granel, María Luz   +5 more
core   +1 more source

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

Journal of Lipid Research, 2004
24S-hydroxycholesterol is a side-chain oxidized oxysterol formed in the brain that is continuously crossing the blood-brain barrier to reach the circulation. There may be an opposite flux of 27-hydroxycholesterol, which is formed to a lower extent in the
Maura Heverin, Nenad Bogdanovic, Dieter Lütjohann, Thomas Bayer, Irina Pikuleva, Lionel Bretillon, Ulf Diczfalusy, Bengt Winblad, Ingemar Björkhem   +8 more
doaj   +1 more source

Side-chain oxidized oxysterols as metabolic regulators in liver and brain [PDF]

, 2014
Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion pathways and its ...
Ali, Zeina M. F.
core   +1 more source

Elimination of Cholesterol in Macrophages and Endothelial Cells by the Sterol 27-Hydroxylase Mechanism [PDF]

Journal of Biological Chemistry, 1997
Amir Babiker, Olof Andersson, Erik Lund, Rui-Juan Xiu, Samir Deeb, Ayeleth Reshef, Eran Leitersdorf, Ulf Diczfalusy, Ingemar Björkhem   +8 more
openaire   +3 more sources

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S., Jungst, C., Jungst, D., Parhofer, K. G., Sauter, G. H., Thiessen, K.   +5 more
core   +1 more source

On the substrate specificity of human CYP27A1

Journal of Lipid Research, 2003
The mitochondrial sterol 27-hydroxylase (CYP27A1) is required for degradation of the C27-sterol side chain in bile acid biosynthesis. CYP27A1 seems, however, to have roles beyond this, as illustrated by patients with a deficient sterol 27-hydroxylase due
Maria Norlin, Sara von Bahr, Ingemar Björkhem, Kjell Wikvall   +3 more
doaj   +1 more source