Results 171 to 180 of about 14,545 (218)

Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review). [PDF]

Int J Mol Med
He Z, Zhang L, Gong S, Yang X, Xu G.
europepmc   +1 more source

Ferroptosis: biology and role in liver disease. [PDF]

J Gastroenterol
Hino K, Nishina S, Yanatori I.
europepmc   +1 more source

Patterns of lipid profile and genetic variations in South Asians. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Rahmanian M.
europepmc   +1 more source

Lipid reprogramming and ferroptosis crosstalk in clear cell renal cell carcinoma: metabolic vulnerabilities and therapeutic targeting. [PDF]

Mol Cancer
Deng Q, Ji Y, Liu J, Wen T.
europepmc   +1 more source

An ATF3 Inducer Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease Through the AMPK and PKA Pathways. [PDF]

Int J Mol Sci
Cheng CF, Yang RB, Chen WT, Chung JF, Ku HC.   +4 more
europepmc   +1 more source

Voluhemins, new inhibitors of sterol O-acyltransferase, produced by Volutella citrinella BF-0440

The Journal of Antibiotics, 2020
New compounds, designated voluhemins A (1) and B (2), are isolated from the culture broth of the fungal strain Volutella citrinella BF-0440 along with structurally related known NK12838 (3). Spectroscopic data, including 1D and 2D NMR, elucidated their structures. Compounds 1-3 have a common indoline-diterpene core and two additional isoprenyl moieties.
Taichi Ohshiro, Haruka Morita, Elyza Aiman Azizah Nur, Kanji Hosoda, Ryuji Uchida, Hiroshi Tomoda   +5 more
openalex   +3 more sources

Pseudopyronine B, an inhibitor of sterol O-acyltransferase, produced by Pseudomonas sp. BYK11209

The Journal of Antibiotics, 2016
The enzyme sterol O-acyltransferase (SOAT, also known as acyl-CoA:cholesterol acyltransferase (ACAT)), an endoplasmic reticulum membrane protein, has important roles in cholesterol regulation in humans.1 SOAT is expected to be a promising target for the development of new anti-atherosclerotic agents.
Aika Suzuki, Takashi Fukuda, Keisuke Kobayashi, Taichi Ohshiro, Hiroshi Tomoda   +4 more
openalex   +3 more sources

Abstract 5468: A pharmacological inhibition of sterol O-acyltransferase 1improves response to enzalutamide in prostate cancer

Cancer Research, 2022
Abstract Prostate cancer (PCa) growth is mediated by androgens via activation of androgen receptor (AR). Accordingly, androgen deprivation therapy (ADT) is the gold standard for the treatment of advanced PCa, but progression to castration-resistant PCa (CRPC) follows. Enzalutamide (ENZ) is an AR antagonist used for the management of CRPC.
Sora Q. Kim, Sagar M. Utturkar, Nadia A. Lanman, Kee‐Hong Kim   +3 more
openalex   +2 more sources