Characterization of Steroid Sulfatase in Human and Mouse Tissues and in the Mouse MC3T3-E1 Pre-Osteoblastic Cell Line [PDF]
, 2007 Steroid sulfatase cleaves the sulfate group from 3Β-hydroxysteroid sulfates. This enzyme is widely distributed among mammalian tissues, and it has been suggested to play a role in the in situ conversion of inactive steroids to active forms in a variety ...
DiFrancesca, Heidi
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The Regulation of Steroid Action by Sulfation and Desulfation [PDF]
, 2015 Steroid sulfation and desulfation are fundamental pathways vital for a functional vertebrate endocrine system. After biosynthesis, hydrophobic steroids are sulfated to expedite circulatory transit.
Arlt, Wiebke +4 more
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CARATTERIZZAZIONE DELL¿ORGANELLO DI NEUROMELANINA DELLA SUBSTANTIA NIGRA UMANA CON APPROCCIO PROTEOMICO [PDF]
, 2012 Substantia nigra is the most affected brain region in Parkinson's disease. Substantia nigra is characterized by strong pigmentation derived by the presence of neuromelanin (NM), a particular melanic pigment that accumulates during aging in neurons in ...
R. Vanna
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Skeletal Muscle Function, Morphology, and Biochemistry in Ts65Dn Mice: A Model of Down Syndrome [PDF]
, 2011 A common clinical observation of persons with Down syndrome at all developmental stages is hypotonia and generalized muscle weakness. The cause of muscle weakness in Down syndrome is not known and there is an immediate need to establish an acceptable ...
Cowley, Patrick Michael
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Degradation of polymeric and particulate organic carbon in biofilms [PDF]
, 2003 Polymeric and particulate organic carbon (POM) are fundamental compounds in the global cycling of carbon, and constitute significant amounts of BOD in municipal wastewater.
Kommedal, Roald
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Characterization and Regulation of Steroid Sulfatase in the Human MG-63 Pre-osteoblastic Cell Line [PDF]
, 2015 The importance of estrogen in bone regulation is exemplified by the reduction in bone density at the onset of menopause. Post-menopausal women have low levels of estrogens, but high levels of inactive sulfated steroids.
Dias, Natasha
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Assessment of dry whey powder as prebiotic in the feeding of laying hens and broilers [PDF]
, 2018 Durante las últimas décadas se ha observado un incremento en la búsqueda de alternativas alimenticias diferentes a los antibióticos que mejoren el rendimiento productivo de gallinas de puesta y pollos de engorde mediante la modulación de las poblaciones ...
García Rodriguez, Aser +2 more
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Substrate inhibition of 17 beta-hydroxysteroid dehydrogenase type 1 in living cells and regulation among the steroid-converting enzymes in breast cancers [PDF]
, 2018 Cette étude a permis de démontrer les fonctions et les mécanismes de la 17bêtahydroxystéroïde déshydrogénase de type 1 (17β-HSD1) et de la stéroïde sulfatase (STS) au niveau du cancer du sein, y compris la cinétique moléculaire et cellulaire, la liaison ...
Han, Hui
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Human Steroid Sulfatase: Inhibitor Studies and Photoaffinity Labeling [PDF]
, 2010 Steroid sulfatase (STS) is considered to be one of the key enzymes contributing to the development of breast cancer. It catalyzes the hydrolysis of inactive sulfated steroids such as estrone sulfate (ES) to inorganic sulfate active steroids such as ...
Phan, Chau-Minh
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DEVELOPMENT OF A PROTEOMIC STRATEGY FOR ANALYSIS OF PLASMA MEMBRANE PROTEINS [PDF]
, 2013 Plasma membrane (PM) proteins play crucial roles in cell signaling and communications, and they are the targets of more than two thirds of drugs currently under development.
Choksawangkarn, Waeowalee
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