A Support Vector Machine Base Model for Predicting Heparin-Binding Proteins Using Biological Metrics and XB Patterns as Features [PDF]
, 2016 Heparin is a highly sulphated and negatively charged polysaccharides belonging to the glycosamino- glycans(GAGs) family. It is widely used in medical treatments as an injectable anticoagulant.
Sirrianni, Joseph W
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Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.Epidemiological studies identify risk factors for Alzheimer’s disease (AD), which induces oxidative stress and inflammation. Pharmaceuticals aimed against the nuclear receptor PPARγ, including TZDs, have been associated with considerable negative consequences in AD treatment.
Tassanee Ongtanasup +4 more
wiley +1 more source
Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease
Oxidative Medicine and Cellular Longevity, Volume 2024, Issue 1, 2024.Approximately 70% of all strokes occur in patients over 65 years old, and stroke increases the risk of developing dementia. The circle of Willis (CoW), the ring of arteries at the base of the brain, links the intracerebral arteries to one another to maintain adequate cerebral perfusion.
Vikram Subramanian +6 more
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Study of the Evolutionary Role of Nitric Oxide (NO) in the Cephalochordate Amphioxus, “Branchiostoma lanceolatum” [PDF]
, 2018 Nitric Oxide (NO) is a gaseous molecule that acts in a wide range of biological processes. NO can be produced by enzymatic and non-enzymatic pathways and, in this scenario, the enzyme Nitric Oxide Synthase (NOS) has a great importance for its exclusive ...
Caccavale, Filomena
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Analyse des Mutationsspektrums bei 46,XY Differences of Sex Development : Nachweis der endocytotischen Rezeptoren LRP2 und LMBR1L sowie des Gens KISS1 [PDF]
, 2023 Für 16 Individuen mit Differences of Sex Development (DSD) wurden Exome sequenziert, um für jeden Fall mittels zugrunde liegender Genmutation die Entstehung des jeweiligen DSD-Phänotyps erklären zu können.
Marko, Hannah Lea
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Characterization of human placental tissue and cell lines for their xenobiotic and steroid disposition potential through quantitative proteomics [PDF]
The placenta is a vital fetal endocrine organ that plays an important role in gas, nutrient, and hormone shuttling between maternal and fetal sides, but much is unknown about the placental functions due to logistical, ethical, and technical challenges in
Kruger, Laken
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A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES [PDF]
, 2015 . Tyramine sulfamate was linked to the trityl chloride resin and this polymeric solid support used to introduce two levels of molecular diversity by formation of peptide bonds.
Diane Fournier +2 more
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Regulation of Steroid Sulfatase by Glucocorticoids in Human Breast Cancer and Bone Cancer Cell Lines [PDF]
, 2007 Steroid sulfatase is an enzyme involved in the conversion of active estrogens and androgens from inactive systemic precursors such as estrone sulfate (E1S) and dehydropiandrosterone sulfate (DHEAS).
Barua, Suman
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Evaluating the effects of PCBs in non-alcoholic fatty liver disease & diabetes and the role of AhR in regulating the hepatic proteome and lipid metabolism. [PDF]
, 2020 Polychlorinated biphenyls (PCBs) are persistent organic pollutants associated with non-alcoholic fatty liver disease (NAFLD) and diabetes. Based on their ability to activate the aryl hydrocarbon receptor (AhR), PCBs are subdivided into two classes ...
Jin, Jian
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정량 단백체학 기술을 이용한 췌관선암 조직에서의 위험군 예측용 다중 바이오마커 어세이 개발 [PDF]
, 2021 학위논문(박사) -- 서울대학교대학원 : 공과대학 협동과정 바이오엔지니어링전공, 2021.8. 김영수.Purpose: Pancreatic ductal adenocarcinoma (PDAC) subtypes have been identified using various methodologies.
손민수
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