Results 21 to 30 of about 15,488 (268)

Treatment of Stiff-Person Syndrome

open access: yes, 2019
Stiff-person syndrome (SPS) is characterized by (1) stiffness of truncal and limb muscles due to continuous co-contracture of agonist and antagonist muscles resulting in hyperlordosis, difficulty bending or turning, and slow, wide-based gait, (2) sudden spasms precipitated by unexpected noises and tactile or visual stimuli, and (3) overt anxiety with ...
Marinos C. Dalakas, Dalakas, M.C.
openaire   +3 more sources

Stiff-Person syndrome

open access: yes, 2022
Background: Stiff-person syndrome is a disorder of the central nervous system that manifests by progressive rigidity together with muscle spasms of the axial and limb muscles. After its initial description in 1956, significant progress has been made in its diagnosis and treatment, although there are still unclear elements about its pathogenesis.
Simon, Florian,
openaire   +2 more sources

Celiac disease with neurological manifestations mimicking stiff‐person syndrome [PDF]

open access: yesJGH Open
Celiac disease (CD), a gluten‐related disease, is a multi‐system rare disorder mainly involving the gastrointestinal tract. The clinical signs of CD are exceedingly heterogeneous, which increases the difficulty of clinical differential diagnosis ...
Jie Niu   +4 more
doaj   +2 more sources

Extracorporeal photopheresis in stiff person syndrome [PDF]

open access: yesFrontiers in Immunology
Yandy Marx Castillo-Aleman   +1 more
doaj   +2 more sources

Stiff Person Syndrome and Gluten Sensitivity [PDF]

open access: yesNutrients, 2021
Stiff person syndrome (SPS) is a rare autoimmune disease characterised by axial stiffness and episodic painful spasms. It is associated with additional autoimmune diseases and cerebellar ataxia. Most patients with SPS have high levels of glutamic acid decarboxylase (GAD) antibodies.
Hadjivassiliou, M.   +4 more
openaire   +3 more sources

Stiff-Person Syndrome [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992
ABSTRACT:The stiff-person syndrome is a disorder of persistent, painful muscle contractions predominately affecting the axial musculature. We describe a patient with this disorder and review its pathophysiology. Molecular biologic and immunologic techniques have recently added to the understanding of the mechanism of this disorder.
M S, Jog, C D, Lambert, A E, Lang
openaire   +2 more sources

Stiff Person-Like Syndrome: An Unusual Presentation of Pituitary Macroadenoma with Panhypopituitarism

open access: yes, 2022
Pituitary adenoma can manifest as pituitary hypofunction, which can cause symptoms of panhypopituitarism. Commonly, symptoms of hormonal deficiencies such as lethargy, weight change, cold intolerance, and sexual dysfunction are reported.
Goh, Kian Guan   +2 more
core   +1 more source

Stiff Person Syndrome and Acetylcholine Receptor Ganglionic Neuronal Antibodies

open access: yesCase Reports in Neurology, 2020
The association between stiff person syndrome and paraneoplastic syndromes has been described, linking intracellular or extracellular antibodies. We describe the case of a 64-year-old woman with stiff person syndrome and positivity for acetylcholine ...
Jacobo Lester   +2 more
doaj   +1 more source

Prevalence of non-neurological autoantibodies and related comorbidities in stiff person spectrum disorders

open access: yesFrontiers in Neurology, 2023
BackgroundStiff Person Syndrome Spectrum Disorders (SPSD) are a group of rare neurological disorders that can present alongside other autoimmune conditions.
Alexandra Balshi   +9 more
doaj   +1 more source

Stiff-person syndrome – a literature review

open access: yesAktualności Neurologiczne, 2019
Stiff-person syndrome, also known as stiff-man syndrome (SMS) or the Moersch–Woltman syndrome, was first described in 1956. The disease is rare. The estimated prevalence in the general population is 1–2 cases/1,000,000, and the annual incidence is 1 case
Karol Jastrzębski
doaj   +1 more source

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