Results 71 to 80 of about 81,429 (302)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Leyes de conservación hiperbólica con términos de relajación stiff y entropía [PDF]
En este trabajo, se estudio el comportamiento de sistemas de leyes de conservación hiperbólico con términos de relajación stiff, reduciendo sistemas, viscosos y no viscosos de leyes de conservación.
Dallos Santos, Dionicio Pastor
core
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
An innovative structural control system is proposed for high-rise buildings. A damping layer is provided between a stiff upper core frame suspended from the top of the main building and a stiff lower core frame connected to the building foundation.
Akira Kawai +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Central Hemodynamics and Arterial Stiffness in Systemic Sclerosis [PDF]
Although microvascular disease is a hallmark of systemic sclerosis (SSc), a higher prevalence of macrovascular disease and a poorer related prognosis have been reported in SSc than in the general population. The simultaneous assessment of prognostically relevant functional properties of larger and smaller arteries, and their effects on ...
Bartoloni E. +8 more
openaire +3 more sources
Initial characterization of stiff skin-like syndrome in West Highland white terriers
BACKGROUND Stiff skin syndrome and systemic or localized scleroderma are cutaneous disorders characterized by dermal fibrosis and present clinically with induration of the skin, with or without joint, internal organ or vascular involvement ...
Doelle, Maren +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
La Mama Theatre
core +3 more sources
The objective of this study is to investigate the influence of the particle size ratio on texture and force transmission in two-dimensional cohesionless binary granular composties by using molecular dynamics (MD) simulations.
Preechawuttipong Itthichai +1 more
doaj +1 more source

