Results 161 to 170 of about 20,823 (293)

Techniques to carry weight loads and resist against bending in conical shells, cases in Kashan [PDF]

, 2017
Danaiee, Ahmad, Korsavi, Sepideh Sadat
core  

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Axial strength of back to back cold formed steel short channel sections with unstiffened and stiffened web holes. [PDF]

Sci Rep
Hussein AB, Papp F.
europepmc   +1 more source

Fracture mechanics as an improvement of fatigue life assessment in orthotropic bridge decks [PDF]

, 2013
De Backer, Hans, Nagy, Wim, Van Bogaert, Philippe   +2 more
core   +1 more source

Study of technology requirements for structures of large launch vehicles. Volume 1 - Summary Final report [PDF]

Aluminum honeycomb structures in launch vehicle ...

core   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Low Noise Structure Design and Experimental Verification of Ship Based on Flexural Wave Band Gap Characteristics. [PDF]

Materials (Basel)
Lu Y, Tang L, Wang C, Peng Z, Xiang L.
europepmc   +1 more source

Optimization of Curvilinear Stiffener Beam Structures Simulated by Beam Finite Elements with Coupled Bending-Torsion Formulation. [PDF]

Materials (Basel), 2023
Patuelli C, Cestino E, Frulla G, Valente F.   +3 more
europepmc   +1 more source

Tailored composite wings with elastically produced chordwise camber [PDF]

Four structural concepts were created which produce chordwise camber deformation that results in enhanced lift. A wing box can be tailored to utilize each of these with composites.
Chang, Stephen, Holl, Michael W., Pickings, Richard D., Rehfield, Lawrence W., Zischka, Peter J.   +4 more
core   +1 more source

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, EarlyView.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source