Results 91 to 100 of about 156,207 (308)
Simvastatin attenuates matrix stiffness-mediated traction forces.
, 2016 Cellular traction forces in endothelial cells increase with matrix stiffness but are attenuated with 1 μM simvastatin treatment. (A) Representative traction stress maps for endothelial cells at each level of matrix stiffness with and without simvastatin ...
John Huynh (704557) +5 more
core +1 more source
Advanced Engineering Materials, EarlyView.Do not let thermal drift and instrument artifacts deceive high‐temperature nanoindentation results. We compare classical Oliver–Pharr and automatic image recognition analyses across steels and a Ni alloy to quantify these effects. Accounting for artifacts reveals systematic softening with temperature, while Cr and Ni additions boost resistance ...
Velislava Yonkova +2 more
wiley +1 more source
APL BioengineeringExtracellular biophysical cues such as matrix stiffness are key stimuli tuning cell fate and affecting tumor progression in vivo. However, it remains unclear how cancer spheroids in a 3D microenvironment perceive matrix mechanical stiffness stimuli and ...
Maulee Sheth +7 more
doaj +1 more source
Stiffness Matrix of Nonlinear FEM Equilibrium Equation
, 2012 For structural stability analysis, either tangent stiffness matrix or secant stiffness matrix is used depending on different situations. In this study, the general mathematic relationship between structural secant and tangent stiffness matrices is ...
Yumei, Li, Jian, Liu, Yun, Tian
core +1 more source
Exploiting Matrix Stiffness to Overcome Drug Resistance
ACS Biomaterials Science & EngineeringDrug resistance is arguably one of the biggest challenges facing cancer research today. Understanding the underlying mechanisms of drug resistance in tumor progression and metastasis are essential in developing better treatment modalities. Given the matrix stiffness affecting the mechanotransduction capabilities of cancer cells, characterization of the
Hakan Berk Aydin +2 more
openaire +4 more sources
Wound Matrix Stiffness Imposes on Macrophage Activation
, 2020 The immune system depends on two major paths-the innate and the adaptive immunity. Macrophage, with its unique features as the first line of immune defense to engulf and digest invaders, serves as the key effector cells integrating those two paths. The dynamic plasticity of macrophage activation during wound repair, inflammation resolution, and tissue ...
Pu, Duann, Pei-Hui, Lin
openaire +3 more sources
Optimization of the Production of Rubber Compounds Using Mathematical Models
Advanced Engineering Materials, EarlyView.Rubber compounds were mixed in a batch internal mixer, and symbolic regression was used to derive mathematical models linking recipe and process parameters to ram path, torque, and mixing quality (incorporation, dispersion, distribution). Subsequent optimization with evolutionary algorithms identified operating conditions that reduce specific energy ...
Anke Bardehle +7 more
wiley +1 more source
A large-stroke compliant joint–based force/displacement integrated sensor
Advances in Mechanical Engineering, 2015 The design methodology and validation of a compliant translational joint–based force/displacement integrated sensor is presented in this article. The stiffness analysis of the large displacement high precision compliant translational joint is developed ...
Xuechao Duan +3 more
doaj +1 more source
Reconstruction of Composite Stiffness Matrix with Array-Guided Wave-Based Genetic Algorithm. [PDF]
Materials (Basel), 2022 Liu M, Zhang Y, Li L, Chen G, Cui F.
europepmc +1 more source
Comparison of several closure approximations for evaluating the thermoelastic properties of an injection molded short-fiber composite [PDF]
, 2007 The accurate prediction of both the elastic properties and the thermal expansion coefficients is very important for the precise simulation of such processes as injection molding of short-fiber polymer-matrix composites.
DRAY, Delphine +2 more
core +1 more source