Results 41 to 50 of about 9,301 (260)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ex vivo biomechanical investigations of combined extra- and intracapsular stabilization in canines with cranial cruciate ligament deficiency

open access: yesFrontiers in Veterinary Science
Intracapsular reconstruction (ICR) has long been recommended as a treatment for cranial cruciate ligament deficiency (CCLD) in dogs, but it has fallen out of favor due to its inferior long-term functional outcomes. These outcomes may be attributed to the
Cheng-Yuan Sun   +2 more
doaj   +1 more source

Artrodese do joelho em cães pela fixação externa Arthrodesis of the stifle in dogs by external fixation

open access: yesCiência Rural, 1998
Sete cães clinicamente sadios sofreram artrodese do joelho direito ou esquerdo. A imobilização foi realizada por meio de fixador externo com pinos de Steinmann e barras de acrílico autopolimerizável.
Beatriz Guilhembernard Kosachenco   +3 more
doaj   +1 more source

GROSS ANATOMICAL STUDY OF THE ARTICULATIO GENUS (STIFLE JOINT) OF THE RABBIT [PDF]

open access: yesVeterinary Medical Journal - Giza, 2004
The aim of the present study was to grossly dissect the stifle joint and to compare its anatomical structures with that of other small domesticated animals. Dissection of twelve stifles joints from six Baladi and New Zealand rabbits of different ages and
F ELNADY
doaj   +1 more source

Histological Findings and T2 Relaxation Time in Canine Menisci of Elderly Dogs—An Ex Vivo Study in Stifle Joints

open access: yesVeterinary Sciences, 2023
Osteoarthritis is a chronic disease that often affects the canine stifle joint. Due to their biomechanical function, the menisci in the canine stifle play an important role in osteoarthritis.
Lena Bunzendahl   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An optimized medial parapatellar approach to the goat medial femoral condyle

open access: yesAnimal Models and Experimental Medicine, 2021
Goats or sheep are the preferred animal model for the preclinical evaluation of cartilage repair techniques due to the similarity of the goat stifle joint to the human knee.
Pieter P. W. vanHugten   +4 more
doaj   +1 more source

Box rest and analgesia compared to arthroscopic debridement for lame horses with hindlimb subchondral lucencies

open access: yesVeterinary Evidence, 2023
Category of research Treatment. Number and type of study designs reviewed Two relevant publications were found, both were retrospective case series. Strength of evidence Weak.
Charlotte Taylor, Julia Dubuc
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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