Results 51 to 60 of about 116,809 (397)

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Погляд на архіви [PDF]

open access: yes, 2010
In a prospective study, the outcome of surgical correction of medial patellar luxation of 70 stifle joints in 55 Pomeranian dogs was evaluated. Trochlear block recession alone was performed in 46 stifle joints, or in combination with tibial tuberosity ...
Hazewinkel, H.A.W.   +4 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

NEW INSIGHTS INTO THE HORSE STIFLE JOINT THROUGH 3D COMPUTED TOMOGRAPHY, SCANNING ELECTRON MICROSCOPY, AND SCANNING ELECTRON MICROSCOPY-ENERGY DISPERSIVE X-RAY ANALYSIS

open access: yesSlovenian Veterinary Research
The study design was prospective and descriptive of the horse stifle joint using CT, sectional anatomy, SEM, and EDX analysis. The 3D rendered-volume reconstruction CT of the horse's stifle joint allows good visualization of the large and small bony ...
Mohamed A. M. Alsafy   +4 more
doaj   +1 more source

Box rest and analgesia compared to arthroscopic debridement for lame horses with hindlimb subchondral lucencies

open access: yesVeterinary Evidence, 2023
Category of research Treatment. Number and type of study designs reviewed Two relevant publications were found, both were retrospective case series. Strength of evidence Weak.
Charlotte Taylor, Julia Dubuc
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Histological Findings and T2 Relaxation Time in Canine Menisci of Elderly Dogs—An Ex Vivo Study in Stifle Joints

open access: yesVeterinary Sciences, 2023
Osteoarthritis is a chronic disease that often affects the canine stifle joint. Due to their biomechanical function, the menisci in the canine stifle play an important role in osteoarthritis.
Lena Bunzendahl   +5 more
doaj   +1 more source

Diagnostic imaging of the canine stifle [PDF]

open access: yes, 2012
C
Gielen, Ingrid   +2 more
core   +1 more source

Ranking of physiotherapeutic evaluation methods as outcome measures of stifle functionality in dogs [PDF]

open access: yes, 2013
BACKGROUND: Various physiotherapeutic evaluation methods are used to assess the functionality of dogs with stifle problems. Neither validity nor sensitivity of these methods has been investigated.
Anna K Hielm-Björkman   +4 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

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