Results 81 to 90 of about 17,673 (293)

Arthroscopy and arthrotomy were equally effective for medial meniscal release but arthroscopy was minimally advantageous at preventing iatrogenic damage to the caudal cruciate ligament: a canine cadaveric study

Frontiers in Veterinary Science
ObjectiveTo compare efficacy of four techniques used for medial meniscal release by medial caudal meniscotibial ligament transection and evaluate associated iatrogenic damage to the medial meniscus, caudal cruciate ligament (CdCL), and articular ...
Dana N. Gale, Steven W. Frederick, Bianca F. Hettlich, Jennifer J. Au, Tatiana Motta   +4 more
doaj   +1 more source

Diagnostics and treatment of canine stifle joint diseases [PDF]

, 2016
The study was conducted in January, 2014 – September, 2015 in veterinary clinic „Pas pumą“. During the investigative work data about 30 dogs sick with stifle joint diseases was gathered. Data on dogs suffering with stifle joint disease was collected in a
Šidlauskaitė, Ieva
core  

Computed tomographic anatomy of the equine stifle joint

, 2011
Objective-To provide a detailed computed tomography (CT) reference of the anatomically normal equine stifle joint. Sample-16 hind limbs from 8 equine cadavers; no horses had evidence of orthopedic disease of the stifle joints.
Erik H. J. Bergman, Bergman, Erik HJ, Katrien Vanderperren, van Bree, Henri, Van der Vekens, Elke, Puchalski, Sarah M, Vanderperren, Katrien, Henri J. J. van Bree, Raes, Els, Els V. Raes, Saunders, Jimmy, Elke Van der Vekens, Sarah M. Puchalski, Jimmy H. Saunders   +13 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Ex vivo preliminary investigation of radiographic quantitative assessment of cranial tibial displacement at varying degrees of canine stifle flexion with or without an intact cranial cruciate ligament

BMC Veterinary Research, 2018
Background The presence of cranial tibial subluxation can aid in the detection of joint instability as a result of CrCL injury. Detection of cranial tibial subluxation has been described using the tibial compression test (TCT) and cranial drawer test ...
Katrina A. Castaneda, Caleb C. Hudson, Brian S. Beale   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Stifle arthrodesis in a feline pelvic limb amputee

Journal of Feline Medicine and Surgery Open Reports
Case summary A domestic shorthair cat presented to the Animal Referral Hospital (Brisbane, Australia) after having the left pelvic limb incorrectly amputated.
Wei Tze Goh, Jarrod Drew
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source