Results 41 to 50 of about 240,300 (249)

Three-Dimensional Simulations of Magnetized Superbubbles: New Insights into the Importance of MHD Effects on Observed Quantities

, 2009
We present three-dimensional magnetohydrodynamic (MHD) simulations of superbubbles, to study the importance of MHD effects in the interpretation of images from recent surveys of the Galactic plane. These simulations focus mainly on atmospheres defined by
A. R. Taylor, Allen, Basu, Braunsfurth, Brown, Callaway, Dennison, Ehlerová, Falle, García-Segura, Gnat, Godunov, Gooch, Gregori, Hayes, Heiles, Heyer, Hillwig, Jeroen Stil, Komljenovic, Kompaneets, Korpi, McClure-Griffiths, McClure-Griffiths, McClure-Griffiths, Nicole Wityk, Norman, Normandeau, Pidopryhora, Rachid Ouyed, Reynolds, Robinson, Rudolph, Staff, Stil, Stil, Taylor, Tomisaka, Vernaleo, West, Westerhout   +40 more
core   +1 more source

Five challenges for public administrations in Europe [PDF]

, 2015
This article examines five ‘challenges’ facing most administrative systems across Europe. The first challenge stems from the increasingly asymmetric nature of European multilevel governance; the second challenge arises from the missed opportunity of ...
Ongaro, Edoardo
core   +3 more sources

Editorial Perspective: The challenge of evaluating ADHD parenting interventions – towards a hybrid approach

Journal of Child Psychology and Psychiatry, EarlyView.
Abstract Behavioural parent training (BPT) has been recommended as part of multi‐modal intervention strategies for children with attention‐deficit/hyperactivity disorder (ADHD). The evaluation of its effectiveness, however, is challenging, as meta‐analyses have indicated a discrepancy between effects on most proximal (MPROX) and probably blinded ...
Saskia van der Oord, Tycho J. Dekkers, Barbara J. van den Hoofdakker, Manfred Döpfner, Edmund Sonuga‐Barke   +4 more
wiley   +1 more source

Impact of stromal tumor-infiltrating lymphocytes (sTILs) on response to neoadjuvant chemotherapy in triple-negative early breast cancer in the WSG-ADAPT TN trial

Breast Cancer Research, 2022
Background Higher density of stromal tumor-infiltrating lymphocytes (sTILs) at baseline has been associated with increased rates of pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) in triple-negative breast cancer (TNBC).
Cornelia Kolberg-Liedtke, Friedrich Feuerhake, Madlen Garke, Matthias Christgen, Ronald Kates, Eva Maria Grischke, Helmut Forstbauer, Michael Braun, Mathias Warm, John Hackmann, Christoph Uleer, Bahriye Aktas, Claudia Schumacher, Sherko Kuemmel, Rachel Wuerstlein, Monika Graeser, Ulrike Nitz, Hans Kreipe, Oleg Gluz, Nadia Harbeck   +19 more
doaj   +1 more source

The HI Chronicles of LITTLE THINGS BCDs: Evidence for External Perturbations in the Morphology and Kinematics of Haro 29 and Haro 36 [PDF]

, 2013
We analyze high angular and velocity resolution HI-line data of two LITTLE THINGS (1) blue compact dwarfs (BCDs): Haro 29 and Haro 36. Both of these BCDs are disturbed morphologically and kinematically.
Ashley, Trisha, Elmegreen, Bruce G., Simpson, Caroline E.   +2 more
core   +1 more source

Novel growth pattern‐specific digital marker of TILs improves stratification of lung adenocarcinoma patients

The Journal of Pathology, Volume 268, Issue 2, Page 164-175, February 2026.
Abstract Lung adenocarcinoma (LUAD) is one of the most prevalent forms of cancer and continues to be associated with high mortality rates, despite recent advances in cancer therapy. Effective risk stratification is critical for guiding treatment decisions and improving our understanding of disease mechanisms. However, current prognostic approaches face
Arwa AlRubaian, Ayesha Azam, Nasir M Rajpoot, Shan E Ahmed Raza   +3 more
wiley   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Polarisation properties of Milky-Way-like galaxies

, 2012
(Abridged) We study the polarisation properties, magnetic field strength, and synchrotron emission scale-height of Milky-Way-like galaxies in comparison with other spiral galaxies.
Beck, Beck, Beck, Beck, Beuermann, Braun, Brown, Brown, Cox, Dumke, Dumke, Fleishman, Gaensler, Gold, Gold, Górski, Han, Haslam, Heald, Heesen, Heesen, Hill, Johnston, Niklas, Nord, Noutsos, Page, Phillipps, Roger, Soida, Sokoloff, Stil, Sun, Sun, Sun, Sun, Taylor, Testori, Van Eck, W. Reich, Waelkens, Wolleben, X. H. Sun   +42 more
core   +1 more source

DNA methyltransferase inhibitors in hematological malignancies and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger, Guillermo Garcia‐Manero, Robert Zeiser, Michael Lübbert   +3 more
wiley   +1 more source

Prognostic role of stromal tumor-infiltrating lymphocytes in locally advanced upper tract urothelial carcinoma: A retrospective multicenter study (TSU-02 study)

OncoImmunology, 2021
Locally advanced upper urinary tract urothelial carcinoma (UTUC) exhibits high recurrence and metastasis rates even after radical nephroureterectomy. Adjuvant immunotherapy can be a reasonable option, and a simple, low-cost, and effective biomarker is ...
Sida Cheng, Wenlong Zhong, Kun Xia, Peng Hong, Rongcheng Lin, Bo Wang, Xinfei Li, Junyu Chen, Zining Liu, Hongxian Zhang, Cheng Liu, Liefu Ye, Lulin Ma, Tianxin Lin, Xuesong Li, Jian Huang, Liqun Zhou   +16 more
doaj   +1 more source