Results 91 to 100 of about 5,580,781 (423)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Differential modulation of performance in insight and divergent thinking tasks with tDCS [PDF]

open access: yes, 2015
While both insight and divergent thinking tasks are used to study creativity, there are reasons to believe that the two may call upon very different mechanisms.
Eimontaite, Iveta   +3 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Biomarkers and Stimulation Algorithms for Adaptive Brain Stimulation [PDF]

open access: yesFrontiers in Neuroscience, 2017
The goal of this review is to describe in what ways feedback or adaptive stimulation may be delivered and adjusted based on relevant biomarkers. Specific treatment mechanisms underlying therapeutic brain stimulation remain unclear, in spite of the demonstrated efficacy in a number of nervous system diseases.
Kimberly B. Hoang   +6 more
openaire   +4 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Improving visuo-motor learning with cerebellar theta burst stimulation: Behavioral and neurophysiological evidence

open access: yesNeuroImage, 2020
The cerebellum is strongly implicated in learning new motor skills. Theta burst stimulation (TBS), a form of repetitive transcranial magnetic stimulation, can be used to influence cerebellar activity.
Giacomo Koch   +13 more
doaj  

The impact of gamma transcranial alternating current stimulation (tACS) on cognitive and memory processes in patients with mild cognitive impairment or Alzheimer's disease: A literature review

open access: yesBrain Stimulation, 2023
Background: Transcranial alternating current stimulation (tACS)—a noninvasive brain stimulation technique that modulates cortical oscillations through entrainment—has been demonstrated to alter oscillatory activity and enhance cognition in healthy adults.
N.R. Nissim   +4 more
doaj  

Comparative studies on yield potential of some hevea clones in Cambodia [PDF]

open access: yes, 2006
Cambodian Rubber Research Institute is carrying out researches on tapping systems to assess the influence of intensity of stimulation on yield at a given tapping frequency 1/2S d/3 7d/7. The objectives of these trials are to determine the yield potential
Chhek, Chan, Hav, S., Lacote, Régis
core  

Utility and lower limits of frequency detection in surface electrode stimulation for somatosensory brain-computer interface in humans [PDF]

open access: yes, 2020
Objective: Stimulation of the primary somatosensory cortex (S1) has been successful in evoking artificial somatosensation in both humans and animals, but much is unknown about the optimal stimulation parameters needed to generate robust percepts of ...
Barbaro, Michael   +9 more
core  

A Method to Evaluate the Stimulation of a Real World Field of View by Means of a Spectroradiometric Analysis [PDF]

open access: yes, 2015
Stimulation elicited by a real world field of view is related to the color, the intensity and the direction of the information reaching the eye: different spectral power distributions of light trigger different responses. An evaluation of the stimulation
Barbalace, Monica   +7 more
core   +2 more sources

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