Results 101 to 110 of about 5,580,781 (423)
New England Journal of Medicine, 2003 BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown.
P. Krack +11 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Brain Stimulation, 2020 Background: Unique amongst brain stimulation tools, transcranial direct current stimulation (tDCS) currently lacks an easy or widely implemented method for individualizing dosage.
Kevin A. Caulfield +8 more
doaj
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
To stimulate the phagocytes [PDF]
Blood, 2015 “There is at bottom only one genuinely scientific treatment for all diseases, and that is to stimulate the phagocytes.” We have come a long way since this declamation by Sir Ralph Bloomfield Bonington in George Bernard Shaw’s 1906 play, The Doctor’s Dilemma.
openaire +4 more sources
Alzheimer’s Research & TherapyIntroduction Numerous studies have demonstrated the effects of transcranial direct current stimulation (tDCS) on cognitive function in the older people. This study further explores the impact of tDCS and its dosage parameters on cognitive enhancement in ...
Thatchaya Prathum +8 more
doaj +1 more source
Efficacy of high frequency switched-mode stimulation in activating Purkinje cells [PDF]
arXiv, 2014 This paper investigates the efficacy of high frequency switched-mode neural stimulation. Instead of using a constant stimulation amplitude, the stimulus is switched on and off repeatedly with a high frequency (up to 100kHz) duty cycled signal. By means of tissue modeling that includes the dynamic properties of both the tissue material as well as the ...
arxiv
Human Reproduction, 2011 The definition presented here represents the first realistic attempt by the scientific community to standardize the definition of poor ovarian response (POR) in a simple and reproducible manner. POR to ovarian stimulation usually indicates a reduction in
A. Ferraretti +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source