Results 51 to 60 of about 5,510,775 (284)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Evidence for Two Types of Task Conflict in a Color-Digit Stroop Task

Journal of Cognition
In the present study, we conducted a Stroop-like task in which the participants were required to decide whether the presented stimulus, which could be either a colored digit or a colored rectangle, consisted of more or less than five colors.
Ronen Hershman, Eldad Keha, Ayelet Sapir, Elisabeth M. Weiss, Avishai Henik, Liane Kaufmann   +5 more
doaj   +1 more source

Perceived and one’s own motion in response priming

Open Psychology, 2020
In response priming, motor pre-activations from a prime to the response to a target can be measured, as a function of whether they require the same (compatible) or different (incompatible) responses.
Bermeitinger Christina, Hackländer Ryan, Kollek Marie, Stiegemeyer Matthis, Tränkner Alexandra E.   +4 more
doaj   +1 more source

Imitation in one's own presence: No specific effect of self-focus on imitation

Acta Psychologica, 2021
Previous studies have reported that imitative responses may be modulated by top-down social factors such as self-focus. However, growing evidence suggests that such social factors may actually modulate domain-general processes such as spatially ...
Divyush Khemka, Narges Ahmadilari, Geoffrey Bird, Caroline Catmur   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Activation, Inhibition, or Something Else: An Exploratory Study on Response Priming Using Moving Dots as Primes in Middle-Aged and Old Adults

Journal of Aging Research, 2018
Response priming refers to the finding that a prime stimulus preceding a target stimulus influences the response to the following target stimulus. With young subjects, using moving dot stimuli as primes indicated faster responses to compatible targets (i.
Christina Bermeitinger, Cathleen Kappes
doaj   +1 more source

Polarity correspondence effect between loudness and lateralized response set

Frontiers in Psychology, 2015
Performance is better when a high pitch tone is associated with an up or right response and a low pitch tone with a down or left response compared to the opposite pairs, which is called the spatial-musical association of response codes (SMARC) effect ...
Seah eChang, Yang Seok eCho
doaj   +1 more source

Stimulus–response compatibility with body parts: a study with hands [PDF]

Experimental Brain Research, 2015
Stimulus-response compatibility (SRC) effects are classified depending on the way that the elements of the stimulus and response sets interact, influencing both the speed and accuracy of the motor response. This is particularly important for social stimuli, such as hands.
Lameira, Allan Pablo, Pereira, Antônio, Fraga‑Filho, Roberto Sena, Gawryszewski, Luiz G.   +3 more
openaire   +3 more sources