Results 41 to 50 of about 11,420 (260)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A computational theory for the learning of equivalence relations

open access: yesFrontiers in Human Neuroscience, 2011
Equivalence relations are logical entities that emerge concurrently with the development of language capabilities.In this work we propose a computational model that learns to build equivalence relations by learning simple conditional rules.
Sergio E Lew   +2 more
doaj   +1 more source

NAMING IN CONDITIONAL DISCRIMINATION AND STIMULUS EQUIVALENCE [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1989
Using a matching‐to‐sample procedure, McIntire, Cleary, and Thompson (1987) taught monkeys the conditional relations A1‐R1‐A1‐R1, A2‐R2‐A2‐R2, A1‐R1‐B1‐R1, A2‐R2‐B2‐R2, B1‐R1‐C1‐R1, and B2‐R2‐C2‐R2, where the first and third terms in each relation refer to the sample and comparison stimuli, respectively, and the second and last terms refer to the ...
openaire   +2 more sources

Stimulus novelty effects during stimulus equivalence testing [PDF]

open access: yesPsychonomic Science, 1971
An analysis is performed on the transfer test data from an experiment which factorially combines percent reward (50% vs 100%) and duration of confinement (2 vs 20 sec) in the presence of cue values from two redundant stimulus dimensions. Rats perform better on test trials which pair the previously negative cues with novel compound cues than on trials ...
Jerry L. Cranford, Keith N. Clayton
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Stimulus Equivalence and Increase of Correct Responses in Addition and Subtraction Problems

open access: yesPaidéia (Ribeirão Preto), 2013
In order to propose interventions that increase correct responses, investigations search for properties of arithmetic problems that hinder its solution. This study assessed whether the formation of two sets of addition and subtraction equivalence classes
Marcelo Henrique Oliveira Henklain   +1 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Aprendizagem de rudimentos de leitura musical com ensino cumulativo e não cumulativo de relações condicionais

open access: yesPsicologia: Teoria e Pesquisa
RESUMO O estudo avaliou o efeito de treino cumulativo de relações condicionais sobre a aprendizagem de rudimentos de leitura musical. Os estímulos foram sequências de notas nas modalidades: sonora (A), notação em clave de sol (B) e figura de teclado (C).
Elenice S Hanna   +2 more
doaj   +1 more source

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