Results 61 to 70 of about 64,868 (308)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Aprendizagem de rudimentos de leitura musical com ensino cumulativo e não cumulativo de relações condicionais

Psicologia: Teoria e Pesquisa
RESUMO O estudo avaliou o efeito de treino cumulativo de relações condicionais sobre a aprendizagem de rudimentos de leitura musical. Os estímulos foram sequências de notas nas modalidades: sonora (A), notação em clave de sol (B) e figura de teclado (C).
Elenice S Hanna, Erick Rôso Huber, Paula Carvalho Natalino   +2 more
doaj   +1 more source

CONTEXTUAL CONTROL OF STIMULUS GENERALIZATION AND STIMULUS EQUIVALENCE IN HIERARCHICAL CATEGORIZATION [PDF]

Journal of the Experimental Analysis of Behavior, 2002
The purpose of this study was to determine whether hierarchical categorization would result from a combination of contextually controlled conditional discrimination training, stimulus generalization, and stimulus equivalence. First, differential selection responses to a specific stimulus feature were brought under contextual control.
Karen, Griffee, Michael J, Dougher
openaire   +2 more sources

Stimulus equivalence relations and equivalence-equivalence relations: effects of the training structure [PDF]

, 2013
En el presente estudio se investiga la influencia de la estructura de entrenamiento en la formación de relaciones de equivalencia y de “equivalencia-equivalencia”.
Argibay, Juan Carlos, Arismendi, Mariana, Fiorentini, Leticia, Iorio, Alberto Andres, Primero, Gerardo, Sanchez, Federico, Segura, Enrique Teodoro, Tabullo, Angel Javier, Vernis, Sergio   +8 more
core   +1 more source

Expanding the boundaries of evaluative learning research: how intersecting regularities shape our likes and dislikes [PDF]

, 2016
Over the last 30 years, researchers have identified several types of procedures through which novel preferences may be formed and existing ones altered. For instance, regularities in the presence of a single stimulus (as in the case of mere exposure) or ...
De Houwer, Jan, Hughes, Sean Joseph, Perugini, Marco   +2 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Emergência de relações numéricas sob controle condicional em crianças surdas

Psicologia: Teoria e Pesquisa
Os estudos sobre classes ordinais têm apresentado diversos achados experimentais para a compreensão das relações entre estímulos em seqüências. O objetivo do presente trabalho foi investigar se esses resultados seriam obtidos em crianças com surdez.
Ruth Daisy Capistrano de Souza, Grauben José Alves de Assis   +1 more
doaj   +1 more source

The GIST of Concepts [PDF]

, 2013
A unified general theory of human concept learning based on the idea that humans detect invariance patterns in categorical stimuli as a necessary precursor to concept formation is proposed and tested.
Vigo , Dr. Ronaldo
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

STABILITY OF FUNCTIONAL EQUIVALENCE AND STIMULUS EQUIVALENCE: EFFECTS OF BASELINE REVERSALS [PDF]

Journal of the Experimental Analysis of Behavior, 2002
Functional equivalence and stimulus equivalence classes were established, reversed, and tested for stability with college students. Functional stimulus classes were established using a task in which students were trained to say nonsense words in the presence of arbitrarily assigned sets of symbols.
Oliver, Wirth, Philip N, Chase
openaire   +2 more sources