Results 151 to 160 of about 112,794 (300)

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Characteristics, Assembly Processes and Stability of Bacterial Communities in Aquatic-Terrestrial Ecotone: A Case Study of Danjiangkou Reservoir, China. [PDF]

Microorganisms
Lyu X, Mei J, Chen H, Yuan H, Dong J, Gao X, Zhang J, Gao Y, Li X.   +8 more
europepmc   +1 more source

Superlattice Architectures for Advancing Photothermal Catalysis: Mechanisms and Applications

Advanced Science, EarlyView.
This paper provides a timely overview of superlattice architectures in photothermal catalysis, with a systematic review on mechanisms at both atomic and macroscopic scales in different processes, challenges, and future opportunities. ABSTRACT Photothermal catalysis has emerged as a powerful strategy to complement photocatalysis by harnessing full ...
Yuzhao Wu, Xiaoguang Duan, Haijun Chen, Hongqi Sun, Jinqiang Zhang, Shaobin Wang   +5 more
wiley   +1 more source

Reinforcement learning-based control co-design of digital twin-enabled full-vehicle active suspension systems. [PDF]

Struct Multidiscipl Optim
Tsai YK, Chen YP, Karkaria V, Chen W.
europepmc   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Nonlinear control of quadrotor UAV under rotor failure for robust trajectory tracking. [PDF]

Sci Rep
Simha A, Ambroziak L.
europepmc   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

Advanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang, Jingze Su, Xiahui Han, Deyong Kang, Xiao Zhang, Fei Xu, Changzu Liu, Junlin Pan, Xingfu Wang, Qiaohui Zhan, Aimin Wang, Feng Huang, Heping Cheng, Wenxi Liu, Ruolan Lin, Jianxin Chen   +15 more
wiley   +1 more source

Dynamic decision-making and differential game analysis of ESG-constrained closed-loop supply chains under cap-and-trade regulation. [PDF]

Sci Rep
Lan H, Si X, Li X, Tang J.
europepmc   +1 more source

A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces

Advanced Science, EarlyView.
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren, Hong Wang, Chak Wang Tse, Yi Zheng, Xi Chen, Wenqi Hu   +5 more
wiley   +1 more source

Modeling the Effects of Gap Cuts on Stand-Level Resilience in Financial and Carbon Sequestration Contexts. [PDF]

Environ Manage
Fibich J, Lange A, Clemen T, Thom D, Knoke T.   +4 more
europepmc   +1 more source