Results 41 to 50 of about 1,105,091 (285)

Probabilistic enhancement of the Failure Forecast Method using a stochastic differential equation and application to volcanic eruption forecasts

open access: yes, 2018
We introduce a doubly stochastic method for performing material failure theory based forecasts of volcanic eruptions. The method enhances the well known Failure Forecast Method equation, introducing a new formulation similar to the Hull-White model in ...
Bevilacqua, Andrea   +5 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Stochastic Control for Intra-Region Probability Maximization of Multi-Machine Power Systems Based on the Quasi-Generalized Hamiltonian Theory

open access: yesEnergies, 2019
With the penetration of renewable generation, electric vehicles and other random factors in power systems, the stochastic disturbances are increasing significantly, which are necessary to be handled for guarantying the security of systems.
Xue Lin, Lixia Sun, Ping Ju, Hongyu Li
doaj   +1 more source

A homomorphism theorem and a Trotter product formula for quantum stochastic flows with unbounded coefficients

open access: yes, 2013
We give a new method for proving the homomorphic property of a quantum stochastic ow satisfying a quantum stochastic differential equation with unbounded coefficients, under some further hypotheses.
Biswarup Das   +9 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The stochastic dynamical behaviors of the gene regulatory circuit in Bacillus subtilis

open access: yesAIP Advances, 2018
In recent years, the gene regulatory circuit in biological systems has attracted a considerable interest. In this paper, we consider the dynamical behaviors of the gene regulatory circuit in Bacillus subtilis, including deterministic system and ...
Liang Wang   +4 more
doaj   +1 more source

Stochastic Order Methods Applied to Stochastic Travelling Waves

open access: yesElectronic Journal of Probability, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tribe, Roger, Woodward, Nicholas
openaire   +3 more sources

Stochastic Block Mirror Descent Methods for Nonsmooth and Stochastic Optimization [PDF]

open access: yes, 2013
In this paper, we present a new stochastic algorithm, namely the stochastic block mirror descent (SBMD) method for solving large-scale nonsmooth and stochastic optimization problems. The basic idea of this algorithm is to incorporate the block-coordinate
Dang, Cong D., Lan, Guanghui
core  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

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