Results 21 to 30 of about 12,651,285 (254)

Use RBF as a Sampling Method in Multistart Global Optimization Method

Signals, 2022
In this paper, a new sampling technique is proposed that can be used in the Multistart global optimization technique as well as techniques based on it.
Ioannis G. Tsoulos, Alexandros Tzallas, Dimitrios Tsalikakis   +2 more
doaj   +1 more source

Using Optimization Techniques in Grammatical Evolution

Future Internet
The Grammatical Evolution technique has been successfully applied to a wide range of problems in various scientific fields. However, in many cases, techniques that make use of Grammatical Evolution become trapped in local minima of the objective problem ...
Ioannis G. Tsoulos, Alexandros Tzallas, Evangelos Karvounis   +2 more
doaj   +1 more source

Applying Bounding Techniques on Grammatical Evolution

Computers
The Grammatical Evolution technique has been successfully applied to some datasets from various scientific fields. However, in Grammatical Evolution, the chromosomes can be initialized at wide value intervals, which can lead to a decrease in the ...
Ioannis G. Tsoulos, Alexandros Tzallas, Evangelos Karvounis   +2 more
doaj   +1 more source

Stochastic programming with multivariate second order stochastic dominance constraints with applications in portfolio optimization [PDF]

, 2014
In this paper we study optimization problems with multivariate stochastic dominance constraints where the underlying functions are not necessarily linear. These problems are important in multicriterion decision making, since each component of vectors can
Xu, Huifu, Meskarian, Rudabeh, Fliege, Jörg   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Evaluation and implementation of measurement uncertainty for determining stationary source emissions: a review

TecnoLógicas, 2018
This paper presents a review of commonly-cited methods for estimating uncertainty in the literature. One of them is the non-stochastic approach proposed by the Guide to the Expression of Uncertainty in Measurement (GUM), which provides an estimation ...
Jhon J. Cárdenas-Monsalve, Andrés F. Ramírez-Barrera, Edilson Delgado-Trejos   +2 more
doaj   +1 more source

Tensor approximation methods for stochastic problems [PDF]

, 2017
Spektrale stochastische Methoden haben sich als effizientes Werkzeug zur Modellierung von Systemen mit Unsicherheiten etabliert. Der Vorteil dieser Methoden ist, dass sie nicht nur Statistiken liefern, sondern auch eine direkte Darstellung der Lösung als
Zander, Elmar Klaus
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source