Results 51 to 60 of about 235,966 (268)
Stochastic modelling of urban structure [PDF]
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2018 The building of mathematical and computer models of cities has a long history. The core elements are models of flows (spatial interaction) and the dynamics of structural evolution. In this article, we develop a stochastic model of urban structure to formally account for uncertainty arising from less predictable events.
L. Ellam +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Explicit solutions for a probabilistic moraine preservation model
Journal of Glaciology, 2016 If a series of glacial advances occurs over the same pathway, the moraines that are now present may constitute an incomplete record of the total history.
PAUL MUZIKAR
doaj +1 more source
Deep stochastic radar models [PDF]
2017 IEEE Intelligent Vehicles Symposium (IV), 2017 Accurate simulation and validation of advanced driver assistance systems requires accurate sensor models. Modeling automotive radar is complicated by effects such as multipath reflections, interference, reflective surfaces, discrete cells, and attenuation. Detailed radar simulations based on physical principles exist but are computationally intractable
Tim Allan Wheeler +3 more
openaire +2 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Fate of a Naive T Cell: A Stochastic Journey
Frontiers in Immunology, 2019 The homeostasis of T cell populations depends on migration, division and death of individual cells (1). T cells migrate between spatial compartments (spleen, lymph nodes, lung, liver, etc.), where they may divide or differentiate, and eventually die (2).
Luis de la Higuera +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Models, systems, networks in economics, engineering, nature and society
Модели, системы, сети в экономике, технике, природе и обществеBackground. Process Мining is a young, dynamically developing field of data science. This data-driven approach to process analytics has already proven its effectiveness and is increasingly gaining popularity in large companies.
M.I. Krevskiy, A.S. Bozhday
doaj +1 more source
Reliability Analysis of Fatigue Failure of Cast Components for Wind Turbines
Energies, 2015 Fatigue failure is one of the main failure modes for wind turbine drivetrain components made of cast iron. The wind turbine drivetrain consists of a variety of heavily loaded components, like the main shaft, the main bearings, the gearbox and the ...
Hesam Mirzaei Rafsanjani +1 more
doaj +1 more source