Results 31 to 40 of about 7,699,774 (306)

Weak Convergence of the Conditional Set-Indexed Empirical Process for Missing at Random Functional Ergodic Data

open access: yesMathematics
This work examines the asymptotic characteristics of a conditional set-indexed empirical process composed of functional ergodic random variables with missing at random (MAR).
Salim Bouzebda   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Modelling stochastic correlation [PDF]

open access: yesJournal of Mathematics in Industry, 2016
This work deals with the stochastic modelling of correlation in finance. It is well known that the correlation between financial products, financial institutions, e.g., plays an essential role in pricing and evaluation of financial derivatives. Using simply a constant or deterministic correlation may lead to correlation risk, since market observations ...
Teng, Long   +2 more
openaire   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Use of Stochastic Models for Short-Term Prediction of Water Parameters of the Thesaurus Dam, River Nestos, Greece

open access: yesProceedings, 2018
The scope of this paper is to evaluate the short-term predictive capacity of the stochastic models ARIMA, Transfer Function (TF) and Artificial Neural Networks for water parameters, specifically for 1, 2 and 3 steps forward (m = 1, 2 and 3).
Antonis Sentas   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

k-Nearest Neighbour Estimation of the Conditional Set-Indexed Empirical Process for Functional Data: Asymptotic Properties

open access: yesAxioms
The main aim of this paper is to improve the existing limit theorems for set-indexed conditional empirical processes involving functional strong mixing random variables.
Youssouf Souddi, Salim Bouzebda
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Functional Conditional Volatility Modeling With Missing Data: Inference and Application to Energy Commodities

open access: yesJournal of Mathematics
This paper explores the nonparametric estimation of the volatility component in a heteroscedastic scalar-on-function regression model, where the underlying discrete-time process is ergodic and subject to a missing-at-random mechanism.
Abdelbasset Djeniah   +2 more
doaj   +1 more source

Modeling and optimizing an AMS with DV policy, waiting servers, impatient customers, and failures: A queueing analysis

open access: yesResults in Control and Optimization
In this paper, we analyze an automated manufacturing system modeled as a queueing system with multiple servers, differentiated vacation (DV) policy, customer impatience, and server failures.
Amina Angelika Bouchentouf   +2 more
doaj   +1 more source

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