Results 41 to 50 of about 1,274,140 (316)

Vulnerability assessment of urban building stock: a hierarchic approach [PDF]

, 2012
In the last decades the evaluation of the seismic risk are of rising concern, considered essential in the activity and definition of strategy planning and urban management.
Costa, A., Ferreira, T., Mendes da Silva, J. A. R., Varum, H., Vicente, R.   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nuclear Multi‐Microsatellite Marker Profiling Provides Clues to Molecular Genetic Diversity in Culture‐Based Caspian Beluga Sturgeon (Huso huso) Brood Stocks: Ecological Mirror for Restoration

Veterinary Medicine and Science
The decreasing natural genetic diversity within intense beluga sturgeon aquaculture presents a complex challenge for culture‐based sturgeon stocks. The present report aims to assess the situation by utilizing advanced capillary electrophoresis (CE) and ...
Mehdi Moghim, Arash Javanmard, Faramarz Lolaei, Mohammad‐Javad Taghavi, Shima Bakhshalizadeh   +4 more
doaj   +1 more source

Depletion Estimation, Stock–Recruitment Relationships, and Interpretation of Biomass Reference Points

Fishes
Stock depletion level is an important concept in the assessment and management of exploited fish stocks because it is often used in conjunction with reference points to infer stock status.
Mark N. Maunder, Kevin R. Piner
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Characterizing the composition of commercial black sea bass (Centropristis striata) catch and discards in the Mid-Atlantic and southern New England regions

Frontiers in Marine Science
Black sea bass (Centropristis striata) is an abundant fishery species that occupies continental shelf waters from the Gulf of Mexico to the Gulf of Maine.
Hannah J. Verkamp, Elizabeth A. Soranno, N. David Bethoney   +2 more
doaj   +1 more source

Considering Other Consumers: Fisheries, Predators, and Atlantic Herring in the Gulf of Maine

Ecology and Society, 2003
After decades of overexploitation and severe depletion, Atlantic herring stocks in waters of the northeastern United States have recovered. Fishery managers now consider the herring resource to be underexploited.
Andrew J. Read, Carrie R. Brownstein
doaj   +1 more source

Choosing the observational likelihood in state-space stock assessment models

, 2016
Data used in stock assessment models result from combinations of biological, ecological, fishery, and sampling processes. Since different types of errors propagate through these processes it can be difficult to identify a particular family of ...
Albertsen, Christoffer Moesgaard, Nielsen, Anders, Thygesen, Uffe Høgsbro   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Evaluation of a spatiotemporal index standardization method for coastal shark species; implications for future stock assessments

Frontiers in Marine Science
IntroductionMethods combining data from spatially limited, independently conducted surveys indicate a preliminary recovery for coastal shark species along the Atlantic.
Kaitlyn A. O’Brien, John K. Carlson, Enric Cortés, William B. Driggers, Bryan S. Frazier, Robert J. Latour   +5 more
doaj   +1 more source