Results 71 to 80 of about 601,557 (262)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Load Characteristics of B-type Metro Vehicle Bogie Frame

open access: yesChengshi guidao jiaotong yanjiu
Objective The international standards adopted in metro vehicle design and verification in China do not fully align with the actual vehicle operating conditions, resulting in the phenomenon of fatigue cracks in some metro vehicle bogie frames before ...
WANG Yuguang   +3 more
doaj   +1 more source

Pengendalian Persediaan Obat dengan Minimum-Maximum Stock Level di Instalasi Farmasi RSUP Dr. Sardjito Yogyakarta

open access: yesJurnal Manajemen dan Pelayanan Farmasi, 2019
Inappropriate inventory control of medicines in hospital can lead to shortage or over stock, which is a problem faced by Dr. Sardjito Hospital Yogyakarta. The aim of this study was to examine the effect of the Minimum-Maximum Stock Level (MMSL) method on
Titik Rahayu Indarti   +2 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Statistical Control Charts: Performances of Short Term Stock Trading in Croatia

open access: yesBusiness Systems Research, 2015
Background: The stock exchange, as a regulated financial market, in modern economies reflects their economic development level. The stock market indicates the mood of investors in the development of a country and is an important ingredient for growth ...
Dumičić Ksenija, Žmuk Berislav
doaj   +1 more source

Audit Operasional: Solusi Atas Biaya DeadStock

open access: yesJurnal Akuntansi, 2018
In manufacturing company, effectiveness and efficiency of inventory control can affect the corporate earnings significantly. According to the observation, the author found a large number of dead stock at PT X.
Christian - Linardo   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Transcriptome analysis of Apostichopus japonicus early in the regeneration process after evisceration

open access: yesInvertebrate Survival Journal
In extreme salt stress and anaerobic conditions, Apostichopus japonicus survives by "evisceration." The species can eject its viscera and create a new organ if the habitat is suitable. The molecular response of A.
BC Wu   +7 more
doaj  

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