Results 31 to 40 of about 141,423 (303)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modelling the impact of policies to reduce environmental impacts in the New Zealand dairy sector [PDF]
, 2011 Agriculture remains a major sector of the New Zealand economy, with the vast majority of farm and food production exported. The accelerating intensification of farming in New Zealand over recent decades raises concern over the current sustainability of ...
Rae, Allan N., Strutt, Anna
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Revista Brasileira de Zootecnia, 2011 The ingestive behavior and performance of female lambs grazing on Marandu pasture submitted to different stocking rates during the rainy and transition season were evaluated.
Luiz Carlos Vieira Júnior +5 more
doaj +1 more source
THE EFFECT OF STOCKING DENSITY ON THE GROWTH AND SURVIVAL RATE OF MILKFISH (CHANOS CHANOS) LARVAE IN FRESHWATER [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2022 Strategies to increase production, including regulating proper density levels, good environmental conditions, and adequate feeding, will increase fish growth.
Septiana S., Sumiarsih, Junaidi
doaj
Grazing Capacity and Stocking Rate
Rangelands, 2000 been increasingly used in range management decisions on both public and private lands in the western United States. They are also becoming more used in developing countries such as South Africa, Australia, Brazil, and Mexico. Range professionals and ranchers are better recognizing that successful range management depends on stocking rangelands so ...
Dee Galt, Francisco Molinar, Joe Navarro
openaire +2 more sources
Private Information, Stock Markets, and Exchange Rates [PDF]
SSRN Electronic Journal, 2009 Explaining exchange rates has long been an important but vexing issue in international economics and finance. In recent years, a number of studies have shown that investors' private information plays a central role in determining exchange rates. We demonstrate in this paper that the private information of investors relevant for exchange rates is ...
Jacob Gyntelberg +3 more
openaire +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Energy use efficiency of livestock farms in a mountain area of Sicily
Italian Journal of Animal Science, 2010 The research aimed to evaluate the performance (in terms of energy) of livestock farms located in a Mediterranean mountain area and characterized by different stocking rates.
Luigi Stringi +5 more
doaj +1 more source