Results 61 to 70 of about 139,727 (259)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Pengaruh Padat Tebar Tinggi Terhadap Kelangsungan Hidup, Konsumsi Pakan Dan Efisiensi Pakan Serta Pertumbuhan Juvenil Lobster Air Tawar (Cherax SP.) [PDF]

open access: yes, 2014
Lobster air tawar (Cherax sp.) merupakan salah satu jenis lobster yang telah dibudidayakan di Indonesia. Padat penebaran merupakan salah satu faktor kunci untuk mencapai produksi yang optimal, terkait dengan budidaya intensif untuk memperoleh produksi ...
Arini, E. (Endang)   +2 more
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Adaptation to Climate Change: Land Use and Livestock Management Change in the U.S. [PDF]

open access: yes
Replaced with revised version of paper 01/26/11Climate Change, Stocking Rate, Land Use, Livestock Management, Environmental Economics and Policy, Land Economics/Use, Livestock Production/Industries,
McCarl, Bruce A., Mu, Jianhong H.
core   +1 more source

Growth and Survival Rate of the Damselfish (Anabas Testudineus ) with Different Stocking Density [PDF]

open access: yes, 2016
The research was conducted on June 1 until July 15, 2015 in Aquaculture Technology Laboratory. The aim of research to determine the growth rate and survival rate of fish damselfish (Anabas testudineus) with different stocking density.
Putra, I. (Iskandar)   +2 more
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

ON THE CHOICE BETWEEN THE STOCKING RATE AND TIME IN RANGE MANAGEMENT [PDF]

open access: yes
A long standing question in range management concerns the relative importance of the stocking rate versus the length of time during which animals graze a particular rangeland.
Batabyal, Amitrajeet A.   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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