Results 111 to 120 of about 104,597 (264)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

There's a Baby in My Stomach!

open access: yes, 2006
This is one of hundreds of 60-second radio spots created by the Center for East Asian Studies (CEAS) for Kansas Public Radio (KPR). The purpose of this outreach program is to introduce the people of Kansas to the culture and current issues of East Asia ...
Tsutsui, William, Hacker, Randi
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Diagram of rat stomach.

open access: yes, 2017
The stomach of the rat is divided into the forestomach (pars proventricularis) and glandular stomach (pars glandularis). For this experiment, the proximal glandular stomach of F344 rat was used after removing forestomach.
Sung Kook Kim (3612251)   +8 more
core   +1 more source

Duplication of the Stomach [PDF]

open access: yesArchives of Disease in Childhood, 1956
W H, GALLOWAY   +2 more
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Stomach contents

open access: yes, 2017
Raw stomach content count data. For every fish, with its given unique identifier number, the number of prey items of each taxonomic group found in the stomach is given.
Thomas, Stephen   +2 more
core   +1 more source

Case Report: Scar‐Like Alterations of the Gastric Mucosa Observed Under Endoscopy in Collagenous Gastritis

open access: yesClinical Case Reports
Collagenous gastritis (CG) is an uncommon disorder of the digestive system, characterized by marked thickening of the subepithelial collagen band and infiltration of inflammatory cells within the lamina propria. The etiology and pathogenesis of CG remain
Qian Luo   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy