Results 101 to 110 of about 626,150 (309)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Extraction of Accurate Stomach Contour Using Approximated Stomach Region [PDF]
, 1999 P(論文)In this paper, the method of stomach extraction is proposed. The stomach contour is automatically and accurately extracted by the characteristics of X-ray image.
43169 +3 more
core +1 more source
陆军军医大学学报Objective To investigate the association between Framingham steatosis index (FSI) and the risk of gallstone disease in order to evaluate its potential as a risk marker and simple screening tool. Methods A cross-sectional study was conducted on 5 705
ZHANG Qizhen, LIU Sutong
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2006 This is one of hundreds of 60-second radio spots created by the Center for East Asian Studies (CEAS) for Kansas Public Radio (KPR). The purpose of this outreach program is to introduce the people of Kansas to the culture and current issues of East Asia ...
Tsutsui, William, Hacker, Randi
core +1 more source
HYPERACIDITY OF THE STOMACH [PDF]
Journal of the American Medical Association, 1914 There is hardly a single condition concerning which opinion and treatment have so much changed during recent years as so-called hyperacidity of the stomach. Practically this term is taken to mean those cases of increasing gastric disturbances which appear at various intervals after the taking of ordinary food or special kinds of nourishment.
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A Case of Large Cell Neuroendocrine Carcinoma of the Stomach with Long Remission after Postoperative Adjuvant Chemotherapy [PDF]
, 2017 Article信州医学雑誌 65(2): 117-123(2017)journal ...
加賀谷, 丈紘 +3 more
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source