Results 81 to 90 of about 104,597 (264)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
A Case of Leiomyosarcoma in Stomach
, 1993 P(論文)A case of leiomyosarcoma of the stomach in a 66-year-old male is reported. The patient was admitted to our hospital because of pain in the upper abdomen as the chief complaint.
賀来, 亨 +11 more
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The Effects of Initial Symptoms on the Prognosis in Patients with Stomach Cancer
, 2015 Aim: The purpose of this study was to determine the effects of initial symptoms on the prognosis in patients with stomach cancer. Methods: The study was carried out first retrospectively reviewing the records of patients with stomach cancer treated ...
Ahmet Bilici +2 more
core +1 more source
The embryonic development of the bovine stomach revisited.
, 2020 The adult anatomy and physiology of the bovine (Bos taurus) stomach have been investigated extensively. Despite the many studies, however, the early development of the stomach has not yet been fully elucidated.
Kalenberg, Christina Alexandra +3 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
World Journal of Surgical OncologyBackground Preoperative assessment of lymph node status is crucial in guiding treatment decisions for gastric cancer (GC) patients. However, it may not always accurately detect occult lymph node metastasis (OLNM).
Zhizhong Xiong +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Eradication of gastric Helicobacter Pylori : are we getting there? [PDF]
, 1995 In 1984 a curved bacillus living in the stomach of patients with gastritis and peptic ulceration was discovered and isolated. This organism named as Helicobacter Pylori (HP), has been shown to play a major role in the causation of duodenal ulcers ...
Pullicino, Edgar
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Frontiers in NutritionBackgroundThe incidence of NAFLD is increasing. Preclinical evidences indicate that modulation of the gut microbiome could be a promising target in nonalcoholic fatty liver disease.MethodA systematic review and network meta-analysis was conducted to ...
Yijia Song +9 more
doaj +1 more source