Results 91 to 100 of about 626,150 (309)
World Journal of Surgical OncologyBackground Preoperative assessment of lymph node status is crucial in guiding treatment decisions for gastric cancer (GC) patients. However, it may not always accurately detect occult lymph node metastasis (OLNM).
Zhizhong Xiong +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Upside-down stomach – results of mini-invasive surgical therapy
, 2011 Aim: The authors evaluate the results of mini-invasive therapy in patients diagnosed with upside-down stomach. Material and methods: From 1998 to 2008, a total of 27 patients diagnosed with upside-down stomach were surgicallytreated at the 1st Department
Katherine Vomackova +4 more
core
Frontiers in NutritionBackgroundThe incidence of NAFLD is increasing. Preclinical evidences indicate that modulation of the gut microbiome could be a promising target in nonalcoholic fatty liver disease.MethodA systematic review and network meta-analysis was conducted to ...
Yijia Song +9 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Eradication of gastric Helicobacter Pylori : are we getting there? [PDF]
, 1995 In 1984 a curved bacillus living in the stomach of patients with gastritis and peptic ulceration was discovered and isolated. This organism named as Helicobacter Pylori (HP), has been shown to play a major role in the causation of duodenal ulcers ...
Pullicino, Edgar
core
The Effects of Initial Symptoms on the Prognosis in Patients with Stomach Cancer
, 2015 Aim: The purpose of this study was to determine the effects of initial symptoms on the prognosis in patients with stomach cancer. Methods: The study was carried out first retrospectively reviewing the records of patients with stomach cancer treated ...
Ahmet Bilici +2 more
core +1 more source
Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation [PDF]
, 2007 <b>Background</b>: The major potential site of acid nitrosation is the proximal stomach, an anatomical site prone to a rising incidence of metaplasia and adenocarcinoma.
Paterson, S. +7 more
core +1 more source