Results 71 to 80 of about 104,597 (264)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Gastrointestinal health anti-diarrheal mixture relieves spleen deficiency-induced diarrhea through regulating gut microbiota

Open Life Sciences
This study evaluated the therapeutic efficacy of the gastrointestinal health anti-diarrheal mixture (GHAM) on diarrhea induced by spleen deficiency, focusing on its modulation of gut microbiota.
Wu Zhengquan, Yao Liuyi, Guo Jun, Xu Zhong, Wang Zhengyan   +4 more
doaj   +1 more source

Global research trends in signaling pathways of spasmolytic polypeptide-expressing metaplasia pathogenesis: a bibliometric analysis

Frontiers in Oncology
BackgroundSignaling pathways associated with spasmolytic polypeptide-expressing metaplasia (SPEM) pathogenesis play a critical role in disease development, particularly in gastric cancer precursor lesions.
Qiumiao Xu, Qiumiao Xu, Zhijiang Dai, Zhijiang Dai, Chengjin Peng, Chengjin Peng, Qinghong Yan, Qinghong Yan, Xiaoting Chen, Xiaoting Chen, Tongwei Liu, Tongwei Liu, Ran Zhang, Guoxin Huang, Xinyao Liu, Jingbin Wang   +15 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine
Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional Constipation (FC) using network pharmacology and experimental research.
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
doaj   +1 more source

Unusual Surgical Repair of Bronchoesophageal Fistula Following Esophagectomy

Diagnostics
Radical esophagectomy remains the only potentially curative option in the treatment of esophageal cancer. However, this procedure is burdened with high morbidity and mortality rates, even in high-volume centers.
Predrag Sabljak, Ognjan Skrobic, Aleksandar Simic, Keramatollah Ebrahimi, Dejan Velickovic, Vladimir Sljukic, Nenad Ivanovic, Milica Mitrovic, Jelena Kovac   +8 more
doaj   +1 more source

THE MENTAL STOMACH [PDF]

The Journal of Nervous and Mental Disease, 1920
n ...
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Food and feeding habits of Synodontis nigrita from the Osun River, SW Nigeria [PDF]

An investigation was conducted into the food and feeding habits of Synodontis nigrita from the Osun River near Epe, Lagos, Nigeria. The food items in the stomach of the S.
Olojo, E.A.A., Osikoya, O.J., Olurin, K.B.   +2 more
core  

Difference in the risk of gastrointestinal manifestations between peritoneal and hemodialysis patients: a systematic review and meta-analysis [PDF]

PeerJ
Objective A large number of patients on dialysis have gastrointestinal (GI) manifestations. However, it remains unclear whether dialysis modality affects their prevalence.
Jiaoyan Li, Jie Liang, Xiaoshuang Shi, Wenjie Lu   +3 more
doaj   +2 more sources