Results 71 to 80 of about 1,082,822 (338)
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
JAMA: The Journal of the American Medical Association, 1903 It is the intention of this paper to present a brief review of the history and the present status of the surgery of the stomach. Although gastrotomy for the removal of a swallowed knife was done as early as 1602 by Matthis of Brandenburg, and gastrostomy for stricture of the esophagus was done by Sedillot in 1849, the surgery of the stomach can very ...
openaire +3 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Pancreaticogastrostomy: Effect of Partial Gastrectomy on the Pancreatic Stump in Rabbits [PDF]
, 1996 To assess the influence of digestive juice on the pancreatic stump when pancreaticogastrostomy was performed after pancreatoduodenectomy, the pancreatic stump was anastomosed to the intact stomach (group I), the stomach after partial gastrectomy (group ...
Nakagawa, Koichi +2 more
core +1 more source
Journal of the American Medical Association, 1912 The subject of this paper is in quotation marks, for this popular but inelegant phrase comes as near expressing my subject as any I can find. In the beginning, let us consider what gas or gases are found in the stomach, although this has been investigated and the knowledge gained has resulted in little or no good.
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Unusual Surgical Repair of Bronchoesophageal Fistula Following Esophagectomy
DiagnosticsRadical esophagectomy remains the only potentially curative option in the treatment of esophageal cancer. However, this procedure is burdened with high morbidity and mortality rates, even in high-volume centers.
Predrag Sabljak +8 more
doaj +1 more source