Results 141 to 150 of about 119,522 (251)

Harnessing Tumor Organoids to Revolutionize Immunotherapy Research

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Immunotherapy has emerged as a revolutionary approach to cancer treatment, yet the lack of robust preclinical testing platforms impedes progress in this field. Tumor organoids, three‐dimensional structures derived from patient‐specific samples, differ from conventional models by faithfully recapitulating the histological, genetic, and ...
Zhen Wang   +7 more
wiley   +1 more source

Geographic Stomatitis

open access: yesActas Dermo-Sifiliográficas (English Edition), 2010
E, Piqué-Duran   +2 more
openaire   +2 more sources

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

Molecular Evolutionary Insights Allow a Sequential Precision Medicine Strategy for Acquired Osimertinib Resistance in EGFR Mutant Non‐Small Cell Lung Cancer: Lessons From Longitudinal Tumor Sampling

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Short Summary This report highlights the importance of rationally‐considered targeted combination treatments, identified by tumour genetic sequencing techniques in tissue and blood, in patients with metastatic NSCLC with EGFR mutation, through the lens of a patient's therapeutic journey.
Foteini Kalofonou   +4 more
wiley   +1 more source

Quantification of Removable Prosthesis Plaque Area Coverage Among Adult Patients: A Systematic Review and Meta‐Analysis

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objective To investigate removable dental prosthesis plaque area coverage assessment methods and conduct a meta‐analysis of prosthesis cleanliness status of adult patients wearing removable dental prostheses, quantified by using computerized planimetric assessments.
Tong Wah Lim   +5 more
wiley   +1 more source

Biodegradable, Breathable, and Skin‐Friendly Solution‐Blown Quercetin Nanofibers for Antiviral Nonwoven Filter

open access: yesEcoMat, Volume 8, Issue 4, April 2026.
A nanofiber filter of quercetin and poly(ethylene oxide), produced through a solution‐blowing technique, serves as an eco‐friendly, high‐performance alternative for antiviral mask filters. The resulting material combines effective particle filtration with excellent breathability, robust mechanical strength, and rapid biodegradability, while also ...
Dogun Park   +13 more
wiley   +1 more source

Distinguishing Pseudotransduction and True Transduction Enables Characterization and Bioengineering of Extracellular Vesicle‐Adeno‐Associated Virus Vectors

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Adeno‐associated virus (AAV) gene therapies have achieved some clinical success, with multiple products reaching regulatory approval. Encapsulation of AAV vectors within engineered extracellular vesicles (EVs) is an emerging strategy which could help overcome challenges including pre‐existing anti‐capsid immunity and the need for controlling ...
Jonathan D. Boucher   +5 more
wiley   +1 more source

Longitudinal Analysis of Oral Potentially Malignant Disorder Conversion to Malignancy

open access: yesThe Laryngoscope, Volume 136, Issue 4, Page 1755-1761, April 2026.
ABSTRACT Objectives Oral potentially malignant disorders (OPMDs) are local and systemic conditions that can result in oral malignancies. We have had an OPMD surveillance program for 25 years covering over 30% of our state's population. More recent electronic health record search techniques have allowed us to analyze over 1500 patients in over a 10‐year
Benjamin Palatnik   +4 more
wiley   +1 more source

Therapeutic Impact of Caffeic Acid Phenethyl Ester and Acyclovir Combination on Human Gingival Fibroblasts (HGF‐1) Infected With Herpes Simplex Type 1 ICP0

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
ABSTRACT Herpes simplex virus Type 1 (HSV‐1) is a prevalent infectious agent globally, often causing oral infections like gingivostomatitis. The ICP0 protein of HSV‐1 exacerbates infection severity by inhibiting antiviral responses. Our study explored how combinations of CAPE (caffeic acid phenethyl ester) and acyclovir influenced immune responses in ...
Merve Sen, Sefa Celik
wiley   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin   +10 more
wiley   +1 more source

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