Semantic Similarity‐Informed Bayesian Borrowing for Quantitative Signal Detection of Adverse Events
Statistics in Medicine, Volume 45, Issue 23-24, October 2026.ABSTRACT We present a Bayesian dynamic borrowing approach to enhance quantitative identification of adverse events in spontaneous reporting systems. The method embeds a robust meta‐analytic predictive prior and incorporates semantic similarity measures (SSMs) to enable weighted information sharing from clinically similar MedDRA preferred terms (PTs) to
François Haguinet +4 more
wiley +1 more source
Pharmacovigilance Analysis of Drug-Induced Stomatitis: Insights From Twenty-One Years of Real-World Data. [PDF]
Int Dent JLiu Z +7 more
europepmc +1 more source
Immunoglobulin a Deficiency in Coeliac Disease: A Scoping Review
United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.ABSTRACT Coeliac disease (CeD) and immunoglobulin A deficiency (IgAD) frequently co‐occur and share a genetic background within the HLA‐DQ2 region. Although this has been known for decades, the underlying mechanisms linking the two conditions remain unclear.
Kristine Bech +4 more
wiley +1 more source
Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with or without hyperhomocysteinemia. [PDF]
J Dent SciWang YP +5 more
europepmc +1 more source
British Journal of Haematology, Volume 209, Issue 4, Page 1664-1672, October 2026.Minimal residual disease (MRD)–guided ibrutinib and venetoclax (IVen) achieved durable remissions and high undetectable MRD (uMRD) rates in patients with high‐risk chronic lymphocytic leukaemia (CLL). Compared with historical ibrutinib monotherapy, IVen was associated with improved progression‐free and overall survival despite presence of complex ...
Maria Kislova +15 more
wiley +1 more source
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with iron deficiency. [PDF]
J Dent SciWang YP +5 more
europepmc +1 more source
Feiwei Heji Enhances Antitumor Immunity by MLL4‐Dependent Regulation of Pyroptosis in Lung Cancer
Cancer Science, Volume 117, Issue 10, Page 2693-2704, October 2026.Feiwei Heji suppresses lung tumor growth by downregulating MLL4 and activating caspase‐1/GSDMD‐associated pyroptosis. This pyroptosis‐related inflammatory response enhances CD8+ T‐cell‐mediated antitumor immunity, revealing an MLL4‐pyroptosis‐immune axis underlying the therapeutic activity of Feiwei Heji.
Nan Cheng +6 more
wiley +1 more source
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome reactivated by the initiation of oral immunotherapy (OIT). [PDF]
Pediatr Allergy ImmunolPelletier A, Couture J, Marois L.
europepmc +1 more source
Effect of Hyaluronic Acid on Palatal Wound Healing—A Randomized Crossover Clinical Trial
Clinical Oral Implants Research, Volume 37, Issue 10, Page 1184-1196, October 2026.ABSTRACT Aim To assess the effect of a hyaluronic acid (HyA) containing gel on patient‐related outcomes (PRO) and wound healing after palatal punch‐biopsy representing a free gingival graft. Material and Methods A punch‐biopsy (6 mm diameter, 2 mm thickness) was harvested from one side of the palate at Day 0 and from the contralateral side at Day 21 ...
Madeleine Dahi +5 more
wiley +1 more source