Results 191 to 200 of about 88,341 (288)

Methotrexate subcutaneous injection for the initial treatment of rheumatoid arthritis can achieve earlier remission compared with oral administration. [PDF]

Med Int (Lond)
Saio Y.
europepmc   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Genome sequence of a historical vesicular stomatitis New Jersey virus isolate collected in 1965 from a naturally infected cow in El Salvador. [PDF]

Microbiol Resour Announc
Valdez F, Velazquez-Salinas L, Fish I, Smoliga GR, Gajewski KP, Davis C, Rodriguez LL, Mire CE, Arzt J.   +8 more
europepmc   +1 more source

Systemic and Mucosal Immune Responses From Serotype‐Switched Viral‐Vectored Ebola Vaccines

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Ebola virus is a highly virulent pathogen causing severe hemorrhagic fever with 25%–90% mortality. The 2014 outbreak infected over 28,000 people, causing 11,325 deaths. Although there is one FDA‐approved vaccine available for limited use, additional vaccines are needed.
Joshua Wiggins, Adthakorn Madapong, Eric Weaver   +2 more
wiley   +1 more source

Antibodies Cross-Reactive with Bundibugyo Virus in Ferrets Vaccinated with Ebola Virus Vaccine. [PDF]

Emerg Infect Dis
Wight J, Schulz H, Banadyga L.
europepmc   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Pattern of Cytopathic Effects Produced by Recent Bangladeshi Field Isolates of PPR Virus in Vero Cells and Preparation of Purified Viral Antigen. [PDF]

Vet Med Int
Siddiqui MSI, Begum JA, Islam MR, Chowdhury EH.   +3 more
europepmc   +1 more source

Isocitrate Dehydrogenase (IDH) Mutations in Hematological Malignancies: Epidemiology, Mechanisms, and Therapeutic Strategies

MedComm – Future Medicine, Volume 5, Issue 3, September 2026.
IDH mutation is an important event in hematological malignancies. This review systematically integrates the basic mechanism of IDH mutations and combines it with the clinical translation of related research progress. It also discusses the application strategies of IDH inhibitors and feasible research directions, with the aim of providing a theoretical ...
Jinkun Xu, Haiying Bai, Lijuan Hu
wiley   +1 more source

Trophoblast cell-surface antigen 2-targeted "sacituzumab tirumotecan": a new approach for epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small cell lung cancer. [PDF]

Transl Lung Cancer Res
Yonesaka K.
europepmc   +1 more source

Native Label‐Free Spectral Biochemical Fingerprinting of an Enveloped Mammalian RNA Virus Reveals Mode of Action of a Virucidal Drug

Small Methods, Volume 10, Issue 18, 23 September 2026.
Deep‐Ultraviolet Resonance Raman (DUVRR) spectroscopy is introduced as a label‐free, non‐invasive analytical workflow for the biochemical fingerprinting of enveloped viruses. By integrating bottom‐up stoichiometric reconstruction with top‐down biochemical extraction, this strategy accurately disentangles complex viral compositions in physiological‐like
Denis Rajnovic, Fatima Matroodi, Lamyaa M. Almehmadi, Tea Carletti, Alessandro Gessini, Igor K. Lednev, Claudio Masciovecchio, Alessandro Marcello, Barbara Rossi   +8 more
wiley   +1 more source