Results 81 to 90 of about 82,858 (250)

Cryptochrome-mediated blue light regulates cell lignification via PbbHLH195 activation of the PbNSC in pear fruits

Molecular Horticulture
The presence of stone cells in pear fruit, caused by lignified secondary cell walls (SCWs), leads to a grainy texture in the fruit flesh, thereby compromising its overall quality.
Qi Wang, Xinyi Wu, Mei Ren, Fanghang Zhang, Yang Zhang, Yueyang Wang, Wen Li, Zhihua Xie, Kaijie Qi, Shaoling Zhang, Katsuhiro Shiratake, Yingying Niu, Shutian Tao   +12 more
doaj   +1 more source

Shape-dependent cellular toxicity on renal epithelial cells and stone risk of calcium oxalate dihydrate crystals

Scientific Reports, 2017
Renal epithelial cell injury causes crystal retention and leads to renal stone formation. However, the effects of crystal shape on cell injury and stone risk remain unclear.
Xin-Yuan Sun, Jian-Ming Ouyang, Kai Yu
doaj   +1 more source

The Stone Cells of the Pear [PDF]

Biochemical Journal, 1926
C, Dorée, E C, Barton-Wright
openaire   +2 more sources

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Comprehensive genome-wide analysis of the pear (Pyrus bretschneideri) laccase gene (PbLAC) family and functional identification of PbLAC1 involved in lignin biosynthesis.

PLoS ONE, 2019
The content and size of stone cell clusters affects the quality of pear fruit, and monolignol polymerization and deposition in the cell walls constitute a required step for stone cell formation.
Xi Cheng, Guohui Li, Chenhui Ma, Muhammad Abdullah, Jinyun Zhang, Hai Zhao, Qing Jin, Yongping Cai, Yi Lin   +8 more
doaj   +1 more source

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

Advanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher, Joachim Schenk, Alessandro Cianciosi, Katherina Hemmen, David Böhringer, Franziska Dusi, Jessica Faber, Philipp Stahlhut, Benedikt Gantert, Emilie Rouenhoff, Annika Gmöhling, Tessa Lühmann, Jörg Teßmar, Jürgen Groll, Silvia Budday, Tomasz Jüngst, Ben Fabry, Katrin G. Heinze, Petra Bauer‐Kreisel, Torsten Blunk   +19 more
wiley   +1 more source

PbUGT72AJ2-Mediated Glycosylation Plays an Important Role in Lignin Formation and Stone Cell Development in Pears (Pyrus bretschneideri). [PDF]

Int J Mol Sci, 2022
Wang H, Feng X, Zhang Y, Wei D, Zhang Y, Jin Q, Cai Y.   +6 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Production of reactive oxygen species by PuRBOHF is critical for stone cell development in pear fruit. [PDF]

Hortic Res, 2021
Wang X, Liu S, Sun H, Liu C, Li X, Liu Y, Deguo Lyu, Du G.   +7 more
europepmc   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source